The citicoline effect of choroidal and scleral thickness in Rattus norvegicus myopia model: A preliminary study
1 Department of Ophthalmology, Faculty of Medicine Universitas Brawijaya Indonesia.
2 Ophthalmology Residence Program of Department Ophthalmology, Faculty of Medicine, Universitas Brawijaya, Indonesia.
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 28(01), 262–267.
Article DOI: 10.30574/gscbps.2024.28.1.0279
Publication history:
Received on 17 June 2024; revised on 27 July 2024; accepted on 30 July 2024
Abstract:
This preliminary study aim to analyze the effect of citicoline to the scleral and choroidal thickness in rattus norvegicus myopia model. This study used lens induced myopia (LIM) method, by giving -10.00 D lens that framed with rubber ring for 3 weeks. The using of ruber as a lens frame has more complication risk than silicone frame. The 300 mg/kgBW citicoline treatment group increase the posterior segment od scleral and choroidal thickness. It could be concluded that citicoline could change the average scleral and choroidal thickness in rattus novergicus myopia model.
Keywords:
citicoline; Choroid; Lens induced Myopia method; Myopia; Sclera
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