Clinicopathological profile of Non-Hodgkin and Hodgkin Lymphoma at the Anatomical Pathology Laboratory of Saiful Anwar General Hospital Malang from January 2018 until May 2023

Eviana Norahmawati 1, 2, Ailen Oktaviana Hambalie 1, 2, *, Diah Prabawati Retnani 1, 2, Agustina Tri Endharti 3 and Nayla Rahmadiani 1, 2

1 Department of Anatomical Pathology, Faculty of Medicine Brawijaya University, Malang, Indonesia.
2 Anatomical Pathology Laboratory, Saiful Anwar General Hospital, Malang, Indonesia.
3 Department of Parasitology, Faculty of Medicine Brawijaya University, Malang, Indonesia.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 25(01), 078–085.
Article DOI: 10.30574/gscbps.2023.25.1.0405
Publication history: 
Received on 18 August 2023; revised on 04 October 2023; accepted on 06 October 2023
 
Abstract: 
Lymphomas are a lymphocyte-driven malignancy that comprise up to 10% of cancers diagnosed in individuals < 20 years of age globally. Malignant lymphomas are divided into Hodgkin Lymphoma (HL) and Non Hodgkin Lymphoma (NHL). In 2019 at United States, more than 82.000 new patients diagnosed with lymphoma. Since the epidemiology of Lymphoma is different across regions and may have change over time, its global distribution pattern, risk factors, and temporal trends need to be assessed for developing preventive measures. The purpose of this study was to determine the frequency of NHL and HL based on histopathological type, age, and gender. This research is a descriptive analytic study. Data were obtained from patients who underwent histopathological and immunohistochemistry examinations at the Anatomical Pathology laboratory of Saiful Anwar General Hospital Malang from January 2018 until May 2023. There are 408 cases of Lymphoma consisting of 56 HL and 352 NHL. In HL, the percentage higher in men, and occurred mostly during 21 – 30 years old age group. The most common histopathological type of HL is Classical Hodgkin Lymphoma, with mostly Nodular Sclerosis subtype. In NHL, the percentage higher in men, and occurred mostly during 51 – 60 years old age group. The most common histopathological type of Non Hodgkin Lymphoma is B cell type.
 
Keywords: 
Non Hodgkin Lymphoma; Hodgkin Lymphoma; Histopatological Type; Age; Gender
 
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