Correlation between therapy modalities and survival of lung cancer patients in Surabaya, Indonesia
1 Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
2 Pulmonology and Respiratory Medicine Department, Dr. Soetomo General Academic Hospital, Universitas Airlangga, Surabaya, Indonesia.
3 Pathological Anatomy Department, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Research Article
GSC Biological and Pharmaceutical Sciences, 2022, 18(01), 041–045.
Article DOI: 10.30574/gscbps.2022.18.1.0022
Publication history:
Received on 04 December 2021; revised on 07 January 2022; accepted on 09 January 2022
Abstract:
Lung cancer is one of the leading causes of death worldwide. Lung cancer treatment are including surgery, chemotherapy, targeted therapy and radiotherapy. Despite therapy modalities mentioned above, lung cancer survival is remained poor. In this research we want to find out the correlation between the current treatment modalities used and the survival of lung cancer patients. Data source is secondary data collected from electronic medical records in oncology polyclinic of Dr. Soetomo General Academic Hospital. Data will be analyzed regarding the correlation between the therapy given and survival of the patients also the correlation between histologic types of lung cancer and therapy given using contingency coefficient. Coefficient we found weak correlation between cancer type and therapy modalities given (p<0.01 and C=0.301) where targeted therapy is related with adenocarcinoma. Moderate correlation between therapy given and survival of the patients (p<0.01, C=0.533). Targeted therapy related with better survival outcome compared to chemotherapy and patient that get only supportive care. Targeted therapy is related with better prognosis compared to chemotherapy and supportive care. Targeted therapy drugs that used in Adenocarcinoma found in this research is mainly targeting EGFR mutation. Squamous cell carcinoma and small-cell carcinoma mainly treated using platinum-based chemotherapy.
Keywords:
Lung cancer; Chemotherapy; Targeted therapy; Survival
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Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
