Determination of the Phytochemical and Antimicrobial properties of Nauclea latifolia Root Smith. (Rubiaceae)
1 Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Chukwuemeka Odumegwu Ojukwu University Igbariam, Anambra State, Nigeria.
2 Department of Pharmacognosy and Traditional Medicine, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University Awka, Anambra State, Nigeria.
3 National Agency for Food and Drugs, Administration and Control, Awka-Ekwulobia Road Agulu, Anambra State, Nigeria.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 23(02), 182–188.
Article DOI: 10.30574/gscbps.2023.23.2.0195
Publication history:
Received on 08 April 2023; revised on 26 May 2023; accepted on 28 May 2023
Abstract:
Nauclea latifolia is a valuable medicinal plant for treating different ailments. Infectious diseases constitute a world health concern.
This work describes the phytochemical analysis and antimicrobial properties of the root of N. latifolia.
Collected root samples were extracted via cold maceration with methanol. The methanol crude extract was fractionated into n-hexane, ethyl acetate, butanol and aqueous fractions. Phytochemical analyses and antimicrobial activity of the methanol extract/ fractions were assessed using agar well diffusion method.
Four different fractions were obtained from the methanol (crude) extract. The phytochemistry carried out showed the presence or absence of certain phytochemicals. The methanol (crude) extract and the different fractions had good antimicrobial properties.
It was concluded that N. latifolia root revealed the presence of phytochemicals and has antimicrobial activity.
Keywords:
Nauclea latifolia; Agar well diffusion assay; Phytochemicals; Antimicrobial
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
