The effect of Moringa leaves on sperm cell maturation level in rat testis metabolic syndrome model

Arsyi Dasa Ramadhan 1, *, Riza Novierta Pesik 2, Dyah Ratna Budiani 2 and Novan Adi Setyawan 2

1 Department of Pathology Anatomi, Universitas Sebelas Maret, Surakarta, Indonesia.
2 Department of Pathology Anatomi, dr. Moewardi Hospital, Surakarta, Indonesia.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 24(01), 018–021.
Article DOI: 10.30574/gscbps.2023.24.1.0260
Publication history: 
Received on 22 May 2023; revised on 30 June 2023; accepted on 03 July 2023
 
Abstract: 
Metabolic syndrome is a combination of several metabolic diseases such as diabetes mellitus, cardiovascular disease and stroke. The ethanolic extract of Moringa Oleifera leaves showed an antioxidant effect in the form of a significant reduction in the production of intracellular ROS (Reactive Oxygen Species) in sperm. This study aims to determine the effect of the ethanolic extract of Moringa leaves (Moringa Oleifera, Lam.) on the level of sperm cell maturation in the testes of wistar rats (Rattus norvegicus) using the Johnson score. And the result, an increase in sperm maturation scores was obtained using the Johnson score. After being given the ethanolic extract of Moringa Oleifera (Moringa Oleifera, Lam). We can concluded that Giving ethanolic extract of Moringa leaves (Moringa Oleifera, Lam) to white rats (Rattus norvegicus) induced by metabolic syndrome was significant to the sperm maturation level of white rats, in the form of increasing sperm maturation scores using the Johnson score.
 
Keywords: 
Metabolic syndrome; Sperm maturation; Johson score; Moringa leaves
 
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