Evaluation of thyroid disorders in cotton growers exposed to pesticides in Satiri department
1 Institut de Recherche en Sciences de la Santé (IRSS), Direction Régional de l’Ouest (DRO), Bobo-Dioulasso, Burkina Faso.
2 Université Nazi Boni (UNB), Bobo Dioulasso, Burkina Faso.
3Département de Laboratoire, service de biochimie, Centre Hospitalier Universitaire Souro SANOU, Bobo-Dioulasso, Burkina Faso.
4 Centre Muraz, Bobo Dioulasso, Burkina Faso.
5 Institut de Recherche en Sciences de la Santé (IRSS), Ouagadougou, Burkina Faso.
6 Unité mixte de Recherche Internationale - Environnement, santé et société (UMI 3189, ESS) CNRS/UCAD/UGB/USTTB/CNRST.
7Institut de l'Environnement et de Recherches Agricoles, Direction Régionale de Recherche Environnementale et Agricole de l’Ouest (INERA/DRREA-O), Farako-Ba, Bobo Dioulasso, Burkina Faso.
Research Article
GSC Biological and Pharmaceutical Sciences, 2020, 13(01), 179-188.
Article DOI: 10.30574/gscbps.2020.13.1.0325
Publication history:
Received on 02 September 2020; revised on 16 October 2020; accepted on 22 October 2020
Abstract:
Cotton farmers are exposed to a variety of pesticide formulations, some of which contain active endocrine disrupting substances. The objective of this study was to investigate the link between pesticide exposure and thyroid disorders in cotton growers.
This was a longitudinal prospective study among cotton producers during and after the 2018/2019 cotton season in the Satiri department. Surveys have been conducted on a cohort of 50 producers to collect socio-demographic and professional information on the producers and the pesticides used. A medical examination of the producers followed by blood samples were carried out during and after the cotton season. The thyroid stimulating hormone (TSH), Free tetra- iodo-thyronine (FT4) and Free tri-iodo-thyronine (FT3) biomarkers were measured on the Cobas®6000 automaton. During the cotton campaign, an overall frequency of 12.00% of dysthyroidism, of which 8.00% of hypothyroidism and 4.00% of hyperthyroidism were recorded. After the campaign, 14.00% dysthyroidism was observed, including 8.00% of hypothyroidism and 6.00% of hyperthyroidism. Also, a significant decrease in TSH concentrations; a significant increase in FT4 and a non-significant decrease in FT3 were observed.
This study does not establish a specific link between exposure to pesticides and thyroid disorders due to the complexity and cocktail effect of pesticides. Rational use of these products is essential to avoid health effects linked to endocrine disruption.
Keywords:
Pesticides; Producers; Cotton; Thyroid; Dysthyroidism
Full text article in PDF:
Copyright information:
Copyright © 2020 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
