Exploring the neuroprotective potential of herbal plants: A comprehensive review

Vishal D. Lahane 1 and Vinayak A. Katekar 2, *

 1 Department of Pharmacology, P R Pote College of Pharmacy, Amravati, India.
2 Department of Quality Assurance, Shraddha Institute of Pharmacy, Washim, Maharashtra, India.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2024, 27(03), 141–148.
Article DOI: 10.30574/gscbps.2024.27.3.0175
Publication history: 
Received on 02 May 2024; revised on 08 June 2024; accepted on 11 June 2024
 
Abstract: 
Neuronal damage resulting from traumatic brain injuries, strokes, and various neurological conditions poses significant challenges to modern medicine. In recent years, there has been a growing interest in the exploration of herbal plants as potential allies in safeguarding and supporting the nervous system. Among these botanical candidates, Ginkgo Biloba and turmeric have emerged as the most extensively researched herbs due to their promising neuroprotective properties. This review paper aims to provide a comprehensive overview of the neuroprotective activity of these herbal plants, shedding light on their mechanisms of action and therapeutic potential. The choice of research methodology in this field is multifaceted, with studies employing in vitro models using cell cultures, animal experiments utilizing mice and rats, and, in some instances, human clinical trials. These diverse research methods have enabled a deeper understanding of how herbal compounds interact with nerve cells, ensuring a rigorous evaluation of their safety profiles, and exploring their applicability as therapeutic interventions. This review paper synthesizes and critically analyzes the available body of evidence, encompassing both preclinical and clinical studies, to present a comprehensive perspective on the neuroprotective effects of Ginkgo Biloba and turmeric. The findings not only illuminate the potential of these herbal remedies in mitigating neuronal damage but also highlight the need for further research to unlock their full therapeutic potential. In an era where the demand for natural and alternative approaches to neurological disorders is on the rise, this review serves as a valuable resource for researchers, healthcare professionals, and the wider community seeking insights into the promising realm of herbal neuroprotection.
 
Keywords: 
Neuroprotection; Curcumin; Neuroprotection; Ginkgo Biloba; Traumatic brain injuries T
 
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