Fluoroquinolones resistant Gram-positive cocci isolated from University of Calabar Teaching Hospital, Nigeria
Department of Microbiology, Faculty of Biological Sciences, University of Calabar, PMB 1115, Calabar, Cross River State, Nigeria.
* Corresponding author
Short Communication
GSC Biological and Pharmaceutical Sciences, 2017, 01(01), 001–005.
Article DOI: 10.30574/gscbps.2017.1.1.0003
Publication history:
Received on 18 August 2017; revised on 05 October 2017; accepted on 09 October 2017
Abstract:
Eighty four clinical samples of Gram-positive cocci isolated from University of Calabar Teaching Hospital, Nigeria were examined for resistance to fluoroquinolones antibiotics using disc diffusion method on Muller Hinton agar. Forty four of the total isolates were Staphylococcus spp. while forty isolates were Streptococcus spp. Resistance rates were highest against ofloxacin 18 (41%) for Staphylococcus spp. and 10 (25%) for Streptococcus spp. followed by sparfloxacin 15 (34%) and 6 (15%) for Staphylococcus spp. and Streptococcus spp., respectively; while resistance to ciprofloxacin was the least 14 (32%) and 4 (10%) for Staphylococcus spp. and Streptococcus spp., respectively. These findings highlight the development of resistance by Gram-positive cocci to fluoroquinolones and suggest for the careful and appropriate administration of these agents as well as infection-control practices.
Keywords:
Fluoroquinolones; Gram-positive cocci; Antibiotic resistance; Staphylococcus; Streptococcus
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Copyright © 2017 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.
