Formulation and evaluation of ointment for acne treatment
Department of Biotechnology, Kumaraguru College of Technology, India.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 23(02), 050–060.
Article DOI: 10.30574/gscbps.2023.23.2.0175
Publication history:
Received on 16 March 2023; revised on 28 April 2023; accepted on 01 May 2023
Abstract:
Acne is a common skin disease that occurs when hair follicles are clogged with dead skin cells or oil from the skin. Propionibacterium acne lives deep inside the cell that secrete digestive enzymes which damage the cell and trigger the inflammation. Manuka honey has anti-inflammatory qualities that helps to prevent redness and swelling. Tea tree oil is a natural alternative for curing acne. The phenol of gallic acid have anti-inflammatory, anti-fungal, antioxidant protection on skin cells against free radicals. Being bioflavonoid, Rutin used in cosmetics as an emollient. Curcumin has an antiseptic and pain-relieving property. This project aims to formulate and evaluate the antibacterial potential of ointment using herbal ingredient such as gallic acid, Rutin and curcumin. They were further subjected to in vitro turbidimetric assay test. The study was further extended to evaluate the minimal inhibitory concentration of formulated ointment.
Keywords:
Propionibacterium acne; Gallic acid; Curcumin; Rutin; Ointment; Antibacterial activity; MIC
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
