Insects as producers of antimicrobial polypeptides: A short review

Ahmed MH Ali 1, 2, Abdur Rauf 3 and Emad M Abdallah 1, *

1 Department of Science Laboratories, College of Science and Arts, Qassim University, Ar Rass, Saudi Arabia.
2 Department of Zoology and Entomology, Faculty of Science, Assiut University, Assiut, Egypt.
3 Department of Chemistry, University of Swabi, Swabi-Anbar-, 23430 KPK, Pakistan.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2020, 12(03), 102-107.
Article DOI: 10.30574/gscbps.2020.12.3.0281
Publication history: 
Received on 29 August 2020; revised on 10 September 2020; accepted on 12 September 2020
 
Abstract: 
The human communities all over the globe, are suffering from emerging and growing of a serious public health problem, the antimicrobial-resistant pathogens, which are resistant to almost all antibiotic classes. This happens in parallel with the decreasing investment in antimicrobial research and development by major pharmaceutical companies as an expensive and high-risk investment. In order to eliminate that phenomenon, the richness and diversity of nature must be taken into account as a cheap and reliable source for antimicrobial drugs. The significance of antimicrobial peptides (AMPs) of insects is widely studied. The source and the method of activity on the insect’s immune system in the susceptible arrangement of these particles have been depicted from alternate points of view. The current short-review is briefly highlighted in this interesting topic. 
 
Keywords: 
Insects; Polypeptides; Antibacterial; Antifungal; Antimicrobial; Antibiotics
 
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