The levels of inhibin A and inhibin B in PCOS patients

Gurbanova Jamila Fazil *, Hasanova Afat Sadig, Maharramova Najiba Tofig and Islamova Jahan Ali

Scientific Research Institute of Obstetrics and Gynecology, Department of Obstetrics, Baku, Azerbaijan. 
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 24(01), 346–349.
Article DOI: 10.30574/gscbps.2023.24.1.0302
Publication history: 
Received on 18 June 2023; revised on 26 July 2023; accepted on 29 July 2023
 
Abstract: 
Background: Polycystic ovary syndrome (PCOS) is one of the main factors leading to infertility and ovulatory dysfunction in women. The aim of the current research is to study the levels of Inhibin A and Inhibin B in women with PCOS, depending on the level of Anti-millerian hormone.
Materials and methods: 30 infertile women (I group) with PCOS (excluding hyperprolactenemia, hypothyreosis, autoimmune thyroiditis) and 30 healthy women (II group) were involved in the study. Hormone profile in blood were determined on the 3rd day of menstruation with ELISA immunoferment analyzer. Results. It was determined an increase in Anti-Müllerian Hormone (AMH) secretion in PCOS patients with hyperandrogenia. Inhibin A and Inhibin B were lower in I group patients.
Conclusion. The detection of Inhibin A and Inhibin B in women with PCOS depending on the level of AMH plays the important role in the evaluation of ovarial reserve in infertile women with hyperandrogenemia. 
 
Keywords: 
Infertility; Hyperandrogenemia; Ovarian reserve; Hormone status
 
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