Loeselia mexicana: Antioxidant and antimicrobial properties by Soxhlet differential extraction
1 Laboratory of Elucidation and Synthesis in Organic Chemistry, Science Institute, BUAP, C.P. 72570, Puebla, Pue., Mexico.
2 Neuroendocrinology Laboratory, FCQ, BUAP, C.P. 72570, Puebla, Pue., Mexico.
3 Herbarium and University Botanical Garden, BUAP, C.P. 72570, Puebla, Pue, México.
4 Science Institute, BUAP, C.P. 72570, Puebla, Pue, México.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 23(02), 115–120.
Article DOI: 10.30574/gscbps.2023.23.2.0196
Publication history:
Received on 09 April 2023; revised on 15 May 2023; accepted on 18 May 2023
Abstract:
Loeselia mexicana or “Espinosilla” commonly known in Mexico is a plant with a great diversity of traditional medicinal uses, especially as an aid in the treatment of superficial wounds, however, said use lacks a scientific basis beyond ethnobotany, so studies of differential extraction that allowed to separate the secondary metabolites according to their polarity to carry out antioxidant tests, associated with the healing process and antimicrobial, associated with avoiding wound infection. The antioxidant potential is divided into two polarities with better results for those extracted by Ethanol (59.38% DPPH and 456.7 mg/kg Folin) and ethyl acetate (63.83% DPPH and 340.1 mg/kg Folin), indicating that both oily and alcoholic has metabolites that prevent skin oxidation; coinciding with the best inhibition halos in Gram negative bacteria. The use of medicinal plants in a traditional way cannot be stopped without affecting the traditions of the Mexican peoples and the world, however, with studies of differential extraction and evaluation of biological activity, it allows to establish scientific bases for its use and to continue to standardize it.
Keywords:
Loeselia Mexicana; Differential extraction; DPPH; Antioxidant; Gram-negative; Antimicrobial activity
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
