Measuring of serum taurine and beta endorphin in women as a pre-early marker for diagnosis of cancer breast
1 Department of zoology, Faculty of Science, Cairo University, Cairo, Egypt.
2 Department of medical Biochemistry, national cancer institute, Egypt.
3 Lecture of clinical pathology, national cancer institute, Egypt.
4 Biological science division, university of Chicago, Illinois, USA.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 25(02), 055–065.
Article DOI: 10.30574/gscbps.2023.25.2.0452
Publication history:
Received on 20 September 2023; revised on 30 October 2023; accepted on 01 November 2023
Abstract:
Objective: Uses of serum level of taurine and beta endorphin as early marker for diagnostic of breast cancer.
Method: We selected our patients from Bahia hospital and cancer institute of Cairo university mainly suffered from positive family history of cancer breast ,acute and chronic mastitis and all women presented with benign mass (fibroma/lipoma) and different stages of cancer breast. We measure serum beta endorphin and taurine, beside complete blood picture, liver function ,kidney function and glucose in blood in all of our patients.
Result: The data showed highly significant change in liver &kidney function between frank control and stages of cancer(p>0.05) that are clearly at latest stages after doses of chemotherapy, but there are slightly change between inflammation and benign.
After we finished all result, we found that there were slightly change of beta-endorphin and taurine at inflammation and benign but further change at stage 1,2 that are continuously change to latest stage
Conclusion: Decreasing of serum taurine level &increasing of serum beta endorphin level considered as a highly sensitive per early marker for breast cancer.
Keywords:
Taurine; Beta Endorphin; Breast cancer; Cancer; Biochemical.
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
