Medicinal plants possessed beneficial therapeutic effects in Alzheimer’s disease and memory deficits

Ali Esmail Al-Snafi *

Dept. of Pharmacology, College of Medicine, University of Thi qar, Iraq.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2021, 17(02), 008–033.
Article DOI: 10.30574/gscbps.2021.17.2.0321
Publication history: 
Received on 24 September 2021; revised on 27 October 2021; accepted on 29 October 2021
 
Abstract: 
Alzheimer's disease is the most common cause of dementia, accounting for an estimated 60% to 80% of cases. The treatment of Alzheimer's disease remains challenging. Many medicinal plants possessed beneficial therapeutic effect inAlzheimer’s disease and memory deficits, by their anti-inflammatory, antioxidant, neuroprotective, NF-κB inhibition, phosphodiesterase inhibition, anti-amyloidogenic, and anticholinesterase activities. In the current article, the medicinal plants with beneficial effects in Alzheimer’s disease and memory deficits were discussed. This article considers not only the therapeutic effect of medicinal plants in AD and memory deficits, but also discussed the mechanisms of their beneficial effects.
 
Keywords: 
Medicinal plants; Alzheimer’s disease; Memory deficits; Mechanisms
 
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