Microneedles: An efficient technique to enhance Transdermal Drug Delivery System
Department of Pharmaceutics, Shri Swami Samarth Institute of Pharmacy, At Parsodi, Dhamangaon Rly, Dist -Amravati (444709) Maharashtra, India.
Review Article
GSC Biological and Pharmaceutical Sciences, 2024, 29(03), 256-266.
Article DOI: 10.30574/gscbps.2024.29.3.0480
Publication history:
Received on 08 November 2024; revised on 18 December 2024; accepted on 21 December 2024
Abstract:
Microneedle technology has emerged as a promising tool for enhancing transdermal drug delivery. This technology involves the use of micron-sized needles to create microchannels in the skin, allowing for the delivery of drugs, vaccines, and other therapeutic agents. The skin's outermost layer, the stratum corneum, is the primary barrier to drug penetration, and microneedles have been shown to effectively bypass this barrier. Various types of microneedles have been developed, including solid, coated, dissolving, and hollow microneedles, each with its own advantages and disadvantages. Microneedles have been used to deliver a range of therapeutic agents, including insulin, vaccines, and cancer therapies. The technology has several benefits, including painless and minimally invasive delivery, improved drug penetration, and reduced side effects. Microneedles have also been shown to enhance the delivery of oligonucleotides, vaccines, and other biological agents. Overall, microneedle technology has the potential to revolutionize the field of transdermal drug delivery, offering new hope for the treatment of various diseases and disorders.
Keywords:
Microneedle technology; Transdermal drug delivery; Minimally invasive; Therapeutic agents; Microneedle fabrication material
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
