Modeling and prediction of dengue cases in the short and long term in Villa Clara, Cuba using climatic variables and objective regressive regression

Carlos M Campos Sánchez 1, Laura A Guillen León 1, David del Valle Laveaga 2, Isbety Acosta Escanaverino 1, Daniel Rodríguez Hurtado 1, Ricardo Osés Rodríguez 3, Rolando J Morales Guerra 4, Frank M Wilford González 4 and Rigoberto Fimia Duarte 4, 5, *

1 University of Medical Sciences of Villa Clara (UCM-VC), Cuba.
2 Academic Area of Health, Maya World University, México.
3 Provincial Meteorological Center of Villa Clara, Cuba.
4 Central University "Marta Abreu" of Las Villas, Villa Clara, Cuba.
5 Faculty of Health Technology and Nursing (FTSE), University of Medical Sciences of Villa Clara (UCM-VC), Cuba.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2022, 18(03), 035–045.
Article DOI: 10.30574/gscbps.2022.18.3.0090
Publication history: 
Received on 23 January 2022; revised on 01 March 2022; accepted on 03 March 2022
 
Abstract: 
Climate has an important influence on infectious diseases and their different modes of transmission. Dengue is among the most relevant for Cuban public health. Due to the pronounced effect that environmental changes can have on the biology of Aedes aegypti, it is very likely that the epidemiology of this arbovirosis will be profoundly influenced by future climate change. The aim of the study was to analyze the possible relationship between meteorological variables and the incidence of Dengue in Villa Clara province, Cuba during the years 2017-2020, and to perform a predictive model of the behavior of the disease during 2021. Retrospective research was carried out in which the possible effects of diversifications of temperature, precipitation, humidity, water vapor tension, atmospheric pressure, wind speed, cloudiness and saturation deficit on the deviations in the epidemiological curves of Dengue infection in Villa Clara (2017-2020) were analyzed to predict the future behavior of the referred entity during the current year. A correlation of the infectious entity with minimum temperature (R=0.332; p=0.023) and water vapor tension (R=0.298; p=0.042) was obtained, as well as an inverse relationship with atmospheric pressure (R=-0.317; p=0.030). It is concluded that a predictive model was obtained for 2021 with high reliability, in which a decrease in the incidence of Dengue is predicted in the month of March until July, but after August to December the values will increase greatly.
 
Keywords: 
Climate change; Dengue; Infectious diseases; Objective Regressive Regression; Climatic variables
 
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