Nanoparticles: A promising approach for enhancing drug delivery and efficacy
Department of Pharmaceutics, Shri Swami Samarth Institute of Pharmacy, At Parsodi, Dhamangaon Rly, Dist Amravati (444709) Maharashtra, India.
Review Article
GSC Biological and Pharmaceutical Sciences, 2025, 30(02), 117-126.
Article DOI: 10.30574/gscbps.2025.30.2.0044
Publication history:
Received on 23 December 2024; revised on 09 February 2025; accepted on 12 February 2025
Abstract:
Nanoparticles (NPs) have emerged as a promising tool for enhancing drug delivery and efficacy with their unique properties, such as small size, high surface area, and biocompatibility, NPs can improve the solubility, permeability, and targeting of drugs. NPs can be synthesized from various materials, including natural or synthetic polymers, lipids, and metals. They offer several advantages, including improved bioavailability, targeted delivery, and reduced toxicity. This review article provides an overview of the types of NPs, their fabrication methods, and their applications in various drug delivery systems, including pulmonary, brain, topical, nasal, and ocular drug delivery. They can be used to treat respiratory diseases, neurological disorders, and cancers. However, there are challenges associated with NP-based drug delivery, including scalable and reproducible manufacturing, safety, and quality control.
Keywords:
Nanoparticles; Pulmonary delivery; Brain delivery; Topical delivery; Nasal delivery; Ocular delivery
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Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
