A novel stability indicating HPTLC method for comparative quantitative estimation of quercetin in herbal preparations
1 Department of Quality Assurance, Vidyabharati College of Pharmacy, Amravati, Maharashtra, India. 444602
2 Department of Pharmaceutical Chemistry, Vidyabharati College of Pharmacy, Amravati, Maharashtra, India. 444602
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 27(02), 262–275.
Article DOI: 10.30574/gscbps.2024.27.2.0178
Publication history:
Received on 05 April 2024 revised on 22 May 2024; accepted on 24 May 2024
Abstract:
This research introduces a novel stability-indicating HPTLC (High-Performance Thin-Layer Chromatography) method for the comparative quantitative estimation of Quercetin in herbal preparations. Through extensive stability studies, the method is validated, providing a robust framework for evaluating Quercetin's stability in diverse herbal formulations. The developed method ensures accurate and reliable quantification of Quercetin, facilitating comparative analysis across various herbal preparations. Additionally, results reveal that Quercetin degraded under most tested conditions, such as acidic, alkaline, oxidative and neutral conditions underscoring the necessity for intervention by experts to eliminate such challenges and ensure product efficacy and quality in the herbal industry.
Keywords:
HPTLC; Quercetin; Stability study; Herbal preparations; Method development and Validation; Quantitative evaluation; Qualitative evaluation; Comparative study
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
