Phytochemical analysis and biological activity of the essential oil of field mugwort: Artemisia campestris L. subsp. glutinosa from the Algerian Sahara

Djamel BOUKHALFA 1, *, Sara MEHENNAOUI 1, Bachir NABTI 1 and Mohamed BELGHOUL 2

1 Laboratory of Pharmacognosy, Faculty of Pharmacy, University of Algiers-1, Algeria.
2 National Office of the Ahaggar Cultural Park (Tamanrasset), Algeria.
 
Research Article
Article DOI: 10.30574/gscbps.2023.23.1.0141
Publication history: 
Received on 22 February 2023; revised on 29 March 2023; accepted on 01 April 2023
 
Abstract: 
This work focuses on the phytochemical study and biological activity (antimicrobial) of the aerial parts of the Artemisia campestris collected from the Ahaggar National Park in southern Algeria. After extraction of the essential oil, chromatographic and biological analyzes were carried out on this species.
The results show an average essential oil yield of 0.6±0.02 ml per 100 g of dry plant. Chromatographic analysis of the essential oil of Artemisia campestris subsp. glutinosa is rich in monoterpene compounds (50.47%), particularly in hydrogenated forms (40.24% of α and β-pinene) and sesquiterpenes (35.75% of Spathulenol (8.47%), β-Eudesmol (4.67%), and Carvomenthene (3.37% )...
The study of antimicrobial activity revealed a remarkable antifungal activity for Candida albicans that could be exploited therapeutically.
 
Keywords: 
Essential oil; Artemesia campestris; GC/MS; Antimicrobial activity; Candida albicans
 
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