Phytochemical analysis, antioxidant and antimicrobial studies of ethanol extract of Coula edulis seed shell

Nkop Ekpeno Josiah *, Onisoman Chuks Zudonu and Charles Chima Onyeji

Department of Chemistry Federal College of Education (Tech), Omoku, Rivers State, Nigeria.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2020, 12(01), 048-053.
Article DOI: 10.30574/gscbps.2020.12.1.0056
Publication history: 
Received on 03 March 2020; revised on 06 July 2020; accepted on 08 July 2020
 
Abstract: 
The phytochemical constituents, antioxidant and antimicrobial potential ethanol extract of Coula edulis (C. edulis) were evaluated. The presence of anthraquinones, steroids phenols, alkaloid, flavonoids, saponins, tannins and deoxy-sugar were ascertained to justify the utilization of this plant in the treatment of diseases. The ethanol extract of Coula edules seed shell was also examined for antioxidant activities and against seven different isolates. Phytochemical profile of the ethanol extract of Coula edulis shell revealed the presence of terpenes, cardiac glycosides, monosaccharides and carbohydrates while alkaloids was found to be absent in the extract. The extract of Coula edules seed shell revealed a very strong antioxidant activity when compared to vitamin C and butylated hydroxytoluene. The antimicrobial result showed that at all concentrations of the seed extract, the growths with almost all the microorganisms were inhibited. The results confirmed high level of antioxidant and antimicrobial properties in ethanol extract of C. edulis contain due to the presence of phytochemical constituents in the plant.
 
Keywords: 
Olacaceae; Coula edulis; Phytochemicals; Antioxidant activity; Antimicrobial
 
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