Prevalence of gynecological and obstetric disorders in patients associated with thyroid dysfunction

Ananya and P Kishore*

Department of Pharmacy Practice, Care College of Pharmacy, Oglapur (v), Damera (m), Warangal (rural), Telangana, India – 506006.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2020, 10(01), 013-017.
Article DOI: 10.30574/gscbps.2020.10.1.0252
Publication history: 
Received on 27 December 2019; revised on 06 January 2020; accepted on 09 January 2020
 
Abstract: 
Thyroid gland is the most vital endocrine gland which plays a major role in growth, development and metabolism of human body. Thyroid dysfunction is an important causative factor of gynecological and obstetric abnormalities. This is an observational study conducted at Obstetrics and Gynecology department of a private hospital in Warangal district. A total of 60 patients were recruited in the present study after satisfying all inclusion and exclusion criteria. Among 255 patients with gynecological complaints, 195 patients (76 %) were euthyroid, 59 patients (23 %) were hypothyroid and 1 patient (01 %) had hyperthyroidism. Among 60 patients with thyroid dysfunction, the most common menstrual disorder observed was oligomenorrhoea. Predominant gynecological disorders associated with thyroid dysfunction were PCOS and Fibroid uterus (51 %). The most common obstetric conditions associated with thyroid disorders are Pregnancy Induced Hypertension (PIH), miscarriage and oligohydramnios all together accounting for 67 %. As thyroid disorders may accompany with alterations in menstrual and reproductive function of women, screening for thyroid dysfunction should be made an integral part of investigations and in the treatment of gynecological and obstetric disorders.
 
Keywords: 
Thyroid dysfunction; Gynecological disorders; Hypothyroidism; Menstrual abnormalities
 
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