A review on antibiotic resistance and way of combating antimicrobial resistance

Shifa Begum1, Tofa Begum2, Naziza Rahman 3 and Ruhul A. Khan4, *

1Department of Genetic Engineering and Biotechnology, University of Chittagong, Chittagong, Bangladesh.
2Research Laboratories in Sciences Applied to Food, Canadian Irradiation Center, INRS-Institut Armand-Frappier, 531, Boulevard des Prairies, Laval, Quebec, Canada, H7V 1B7.
3Department of Microbiology, University of Dhaka, Bangladesh.
4Institute of Radiation and Polymer Technology, Atomic Energy Research Establishment, Savar, Dhaka, Bangladesh.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2021, 14(02), 087-097.
Article DOI: 10.30574/gscbps.2021.14.2.0037
Publication history: 
Received on 13 January 2021; revised on 07 February 2021; accepted on 09 February 2021
 
Abstract: 
Antibiotics are widely used most effective medication since the twentieth century against bacterial infections (Tetanus, Strep Throat, Urinary Tract Infections, etc.) and thus save one’s life. Before 20th-century infectious disease played the main role in the death. Thus, antibiotics opened a revolutionary era in the field of medication. These cannot fight against viral infections. Antibiotics are also known as an antibacterial that kill or slow down bacterial growth and prohibit the bacteria to harm. Resistance comes as a curse with antibiotics that occurs when bacteria change in some way that reduces or eliminates the effectiveness of drugs, chemicals or other agents designed to cure or prevent infections. It is now a significant threat to public health that is affecting humans worldwide outside the environment of the hospital. When a bacterium once become resistant to antibiotic then the bacterial infections cannot be cured with that antibiotic. Thus, the emergence of antibiotic-resistance among the most important bacterial pathogens causing more harm. In this context, the classification of antibiotics, mode of action of antibiotics, and mechanism of resistance and the process of overcoming antibiotic resistance are discussed broadly.
 
Keywords: 
Antibiotic; Classification of antibiotic; Mode of action; Resistance mechanism
 
Full text article in PDF: 
Share this