A review on suppositories

Chandra Sekhara Rao G *, Yasmitha B, Pallavi A, Devaki D and Vasundhara A

Vignan Institute of Pharmaceutical Technology, Beside VSEZ, Duvvada, Visakhapatnam-530049, India.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2023, 25(01), 186-192.
Article DOI: 10.30574/gscbps.2023.25.1.0429
Publication history: 
Received on 06 September 2023; revised on 17 October 2023; accepted on 19 October 2023
 
Abstract: 
Suppositories are pharmaceutical dosage forms that hold a crucial place in the realm of drug delivery. This review provides a comprehensive introduction to suppositories. This article explores the various aspects of suppository formulations and therapeutic applications. This review emphasizes the significance of suppositories as a valuable drug delivery option and the role they play in addressing specific patient needs. It also discusses the fundamental components of suppositories, including bases and active pharmaceutical ingredients, along with the methods of suppository preparation. The development and formulation of suppositories require a deep understanding of various factors, including base selection, drug compatibility, and patient preferences. The choice of base impacts the release and absorption characteristics of the drug, making it a pivotal consideration in suppository design. Their significance lies not only in their unique mode of administration but also in their ability to offer solutions for specific patient needs, including cases of nausea, vomiting, or difficulties with oral medication.
 
Keywords: 
Suppositories; Types of Bases; Methods of Preparation; Evaluation tests
 
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