Review on synthetic study of benzotriazole
Department of Pharmaceutical Chemistry, Priyadarshini J. L. College of Pharmacy, Nagpur-440016, (Maharashtra), (India).
Review Article
GSC Biological and Pharmaceutical Sciences, 2020, 11(02), 215-225.
Article DOI: 10.30574/gscbps.2020.11.2.0137
Publication history:
Received on 11 May 2020; revised on 20 May 2020; accepted on 22 May 2020
Abstract:
Benzotriazole is nitrogen containing heterocycle derivative containing three nitrogen atoms at 1st, 2nd, 3 rd positions. Lone pairs of each nitrogen atom are present in unshared form. The unshared lone pair of electrons enables five-membered ring to exhibit that can exist in tautomeric forms. Benzotriazole belongs to a fused heterocycles, which has a benzene ring fused with with a traizole ring. Benzotriazole and its derivatives have great significance in medicinal chemistry. The derivatives are used by several chemists for therapeutic conditions. The current paper concise several synthetic methods utilized for synthesizing derivativeswhich acts as antimicrobials, antibacterial, antifungal, antiviral, antitubercular, anticancer, anti-inflammatory, anticonvulsant, analgesic and antioxidant agents. The article will also help the researchers to understand the structure activity relationships and improvise the conceptsin their researches.
Keywords:
Benzotriazole; Antimicrobial; Anticancer; Antifungal; Fused heterocycles
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Copyright © 2020 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
