A review on transdermal drug delivery system
Department of Pharmaceutics, Centre for Pharmaceutical Sciences, JNTUH UCEST, JNTUH, Hyderabad, Telangana-500085, India.
Review Article
GSC Biological and Pharmaceutical Sciences, 2023, 22(02), 245–255.
Article DOI: 10.30574/gscbps.2023.22.2.0053
Publication history:
Received on 01 January 2023; revised on 15 February 2023; accepted on 17 February 2023
Abstract:
In order to produce systemic effects, transdermal drug delivery systems (TDDS), commonly referred to as "patches," are dosage forms that are intended to spread a therapeutically active amount of medicine across the skin of a patient. Drugs that are applied topically are delivered using transdermal drug delivery devices. These are pharmaceutical preparations of varying sizes, containing one or more active ingredients, intended to be applied to the unbroken skin in order to deliver the active ingredient after passing through the skin barriers, and these avoid first pass metabolism. Today about 74% of drugs are taken orally and are not found effective as desired. To improve efficacy transdermal drug delivery system was emerged. In TDDS the drug easily penetrates into the skin and easily reaches the target site. To get around the problems with medicine delivery via oral route, transdermal drug delivery systems were developed. These systems have been utilized as secure and reliable drug delivery systems since 1981.
Keywords:
Transdermal drug delivery system; Patch; Topical administration; Systemic circulation
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
