Serum uric acid level among diabetic, hypertensive and diabetic-hypertensive patients attending specialist hospital Sokoto

Yale Bala Malam 1, *, Yeldu Muhammed Haruna 1, Dallatu Kabiru Muhammed 1 and Danjuma Abubakar 2

1 Department of Chemical Pathology, School of Medical Laboratory Sciences, Usmanu Danfodiyo University, PMB 2346, Sokoto, Nigeria.
2 Department of Chemical Pathology, Federal Medical Center Bida, Niger State, Nigeria.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2020, 010(01), 109-117.
Article DOI: 10.30574/gscbps.2020.10.1.0010
Publication history: 
Received on 13 January 2020; revised on 22 January 2020; accepted on 23 January 202
 
Abstract: 
Elevated serum uric acid is associated with metabolic disorders such as insulin resistance, hypertension, diabetes, dyslipidaemia and also increases the risk of cardiovascular disease. This study evaluated serum uric acid and fasting plasma glucose in diabetic, hypertensive and diabetic-hypertensive patients. This study consist of 120 subjects including 30 diabetics, 30 hypertensives, 30 diabetic-hypertensive patients and 30 age- and sex-matched controls. The mean serum uric acid was significantly (p<0.001) higher in diabetic, hypertensive and diabetic-hypertensive patients when compared with those of controls. While the mean values of fasting plasma glucose were significantly (p<0.001, p=0.007 and p<0.001) higher in diabetic, hypertensive and diabetic-hypertensive patients respectively when compared with those of controls. It was concluded from the finding of this study that, serum uric acid level and fasting plasma glucose increases significantly in diabetic, hypertensive and diabetic-hypertensive patients. It is recommended that serum uric acid and plasma glucose should be included as a routine investigation for the management of these groups of individuals to avoid the risk of cardiovascular diseases.
 
Keywords: 
Uric acid; Glucose; Hypertension; Diabetes; Patients; Controls
 
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