Short notes on molecular mechanisms behind antimicrobial drug resistance
Department of Pharmacy, Jahangirnagar University, Dhaka-1342, Bangladesh.
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 24(03), 001–009.
Article DOI: 10.30574/gscbps.2023.24.3.0353
Publication history:
Received on 23 July 2023; revised on 29 August 2023; accepted on 01 September 2023
Abstract:
Infectious disease mortality have occurred often, raising public awareness of their hazards and advancing global antibiotic research. On the other hand, higher antibiotic levels in natural ecosystems are a result of increased antibiotic demand and use. Gene mutations causing antibiotic resistance in bacterial populations were brought on by natural selection and adaption. The emergence of antibiotic-resistant bacteria was caused by the spread of antibiotic resistance genes in ecosystems, which resulted in a number of antibiotic-resistant diseases on a global scale. An overview of the history of antibiotic discovery, antibiotic use, and antibiotic resistance mechanisms is given in this review study. Bioinformatics is also used to combat antibiotic resistance. To control bacteria that no longer respond to the therapy, the creation of new medications appears to be the primary requirement today.
Keywords:
Drug resistance; Antibiotic; Bioinformatics; Mutations
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0