Synthesis and antimicrobial screening of some Schiff bases
1 Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India.
2 Department of Biosciences, Saurashtra University, Rajkot, Gujarat, India.
3 Department of Chemistry, Christ College, Rajkot, Gujarat, India.
GSC Biological and Pharmaceutical Sciences, 2019, 09(03), 099-108.
Article DOI: 10.30574/gscbps.2019.9.3.0232
Publication history:
Received on 06 December 2019; revised on 18 December 2019; accepted on 19 December 2019
Abstract:
Some new Schiff bases were synthesized from pyrazolo aldehydes and triazoles and their structures were confirmed by IR, 1H NMR, and Mass spectral data. All these synthesized compounds were tested in vitro for their antimicrobial potential in N, N-dimethyl formamide and dimethyl sulfoxide by agar well diffusion method. The antimicrobial strains were of Gram positive bacteria, Gram negative bacterial and fungal strains.
Keywords:
Schiff bases; Triazole; Antimicrobial activity; Agar-well diffusion method; N N-dimethyl formamide
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