Systemic validation of Herbo- mineral formulation Udara Noi Nivarana Thiravagam by instrumental analysis

ETHEL SHINY S 1, *, JAYALAKSHMI J 2 and BHARATH CHRISTIAN CBS 3

1 Department of Gunapadam – Marunthiyal(Pharmacology), 3Santhigiri Siddha Medical College, Kerala University of Health Sciences, Pothencode, Thiruvananthapuram, Kerala, India.
2 Department of Gunapadam – Marunthakaviyal (Pharmaceuticals), 2Sivaraj Siddha Medical College, The Tamilnadu Dr. M.G.R. Medical University, Salem, Tamilnadu, India.
3 Department of Maruthuvam(Medicine), Santhigiri Siddha Medical College, Kerala University of Health Sciences,
Pothencode, Thiruvananthapuram, Kerala, India.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 24(03), 218–223.
Article DOI: 10.30574/gscbps.2023.24.3.0381
Publication history: 
Received on 04 August 2023; revised on 13 September 2023; accepted on 15 September 2023
 
Abstract: 
Siddha medicine is a complementary system of medicine, drawing global attention in recent times since it contains many formulations, able to treat and cure many diseases even degenerative disorders with no adverse or side effects. It comprises thirty-two types of internal formulations with distinct preparation techniques mentioned in various classical Siddha texts. These traditional medicines require newer standardization techniques to prove their safety and efficacy. Udara Noi Nivarana Thiravagam is a Siddha herbo-mineral formulation used for the treatment of peptic ulcer disease (PUD). This work was proposed to formulate and standardize Udara Noi Nivarana Thiravagam as per the guidelines set forth by PLIM. Udara Noi Nivarana Thiravagam was standardized by various parameters like FT-IR, ICP-OES and GC-MS. All parameters showed desirable results concerning the standard limits. The set parameters were sufficient to evaluate Udara Noi Nivarana Thiravagam and this could be used as reference standards for the quality control and quality assurance of the drug.
 
Keywords: 
Siddha; Udara Noi Nivarana Thiravagam; FT-IR; ICP-OES; GC-MS
 
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