UV spectrophotometric method for estimation of famciclovir in pharmaceutical formulation
Department of Pharmaceutical Analysis, Srikrupa Institute of Pharmaceutical Sciences, Siddipet-502 277 (TS).
Research Article
GSC Biological and Pharmaceutical Sciences, 2021, 16(03), 267–273.
Article DOI: 10.30574/gscbps.2021.16.3.0272
Publication history:
Received on 10 August 2021; revised on 23 September 2021; accepted on 25 September 2021
Abstract:
A simple, rapid, sensitive and accurate UV-spectrophotometric method has been developed for the estimation of Famciclovir in pharmaceutical formulation. The method was developed by using 0.1 N HCl as a solvent and absorbance was measured at 312 nm. The drug exhibited the linearity in the concentration range of 2-12 μg/ml with a correlation coefficient of 0.9978. The % recovery of the drug was found to be 98.62 % - 100.5 %. The method was validated as per ICH guidelines. The proposed method is economical and sensitive for the estimation of Famciclovir in bulk and tablet dosage form.
Keywords:
Famciclovir; 0.1 N HCl; UV-spectrophotometric method; ICH guidelines
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Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
