Verification of the analytical performance of the serum glucose assay on the Abbott Alinity ci®

Issam Mokhtari 1, 2, *, Imad-Eddine Elkhamlichi 1, 2, Zainab Kajeiou 1, 2, Salwa Dahmani 1, 2, Abderrazak Saddari 1, 2, El Houcine Sebbar 1, 2 and Mohammed Choukri 1, 2

1 Mohammed First University, Faculty of Medicine and Pharmacy of Oujda, Morocco.
2 Biochemistry laboratory of Mohammed VI University Hospital, Oujda, Morocco.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 24(03), 068–074
Article DOI: 10.30574/gscbps.2023.24.3.0371
Publication history: 
Received on 28 July 2023; revised on 05 September 2023; accepted on 08 September 2023\
 
Abstract: 
The precision and reliability of the serum glucose assay on the Abbott Alinity ci® analyzer were systematically evaluated. The study was conducted over 30 days in the biochemistry laboratory of Mohammed VI University Hospital. Two phases were carried out: reproducibility assessment involving daily measurements across low, medium, and high glucose levels, and repeatability testing involving 30 replicates per sample. The hexokinase enzymatic approach was employed for glucose quantification. Data analysis utilized the BYG middleware and complied with FSCB and RICOS standards. For reproducibility, the coefficient of variation (CV) values were low, ranging from 1.49% to 1.84%. Repeatability CV values were even lower, varying from 0.34% to 0.94%. Results aligned well with quality control limits, confirming the assay's consistency and precision. This study underscores the robustness and reliability of the hexokinase method on the Alinity ci® platform for serum glucose analysis, with implications for accurate patient care. By adhering to strict analytical performance verification, laboratories ensure dependable clinical outcomes. This research contributes to the foundation of knowledge supporting serum glucose measurement reliability.
 
Keywords: 
Serum glucose assay; Abbott Alinity ci analyzer; Precision; Reliability; Biochemistry laboratory; Mohammed VI University Hospital; Reproducibility assessment; Repeatability testing; Hexokinase enzymatic method
 
Full text article in PDF: 
 
Copyright information: 
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

 

Share this