Verification of the insulin dosage method using Abbott Alinity ci®: experience of the biochemistry laboratory, CHU Mohammed IV Oujda, Morocco
1 Central Laboratory, Mohammed VI University Hospital, Oujda, Morocco.
2 Mohammed First University, Faculty of science of Oujda, Morocco.
3 Mohammed First University, Faculty of Medicine and Pharmacy of Oujda, Morocco.
Research Article
GSC Biological and Pharmaceutical Sciences, 2024, 28(01), 164–170.
Article DOI: 10.30574/gscbps.2024.28.1.0271
Publication history:
Received on 12 June 2024; revised on 20 July 2024; accepted on 22 July 2024
Abstract:
Introduction: The aim of our study was to evaluate the analytical performance of the insulin dosage method, which was performed by the Alinity ci® automated system in the biochemistry laboratory of the Mohammed VI University Hospital in Oujda.
Insulin acts as an essential role in regulating the body's energy supply, mainly by balancing blood sugar levels via the storage of glucose in the liver, muscles and adipose tissue.
Materials and methods: We carried out a study of the performance of the Alinity ci® automated system, assessing repeatability and reproducibility in accordance with the COFRAC GTA 04 accreditation technical guide, which meets the quality requirements of standard ISO 15 189.
Results: The results of our study show satisfactory repeatability for the three levels (Low; Medium; High) with CV1 = 2.44 %, CV2 = 1.76 %, CV3 = 1.33 %. The reproducibility of insulin was also satisfactory, with respect to the coefficient of variation (CV) for the three levels (Low, Medium, High), respectively CV1 = 3.16 %, CV2 = 5.78 %, CV3 = 2.88 %.
Conclusion: The reliability of our laboratory's insulin assay results is demonstrated by the satisfactory results obtained in our study, which comply with RICOS and FSCB recommendations.
Keywords:
Insulin; Verification; Repeatability; Reproducibility; Alinity ci®
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