Association of Helicobacter pylori infection and vitamin B12 deficiency
Department of Microbiology, College of Medicine, Diyala University, Diyala, Iraq.
Review Article
GSC Biological and Pharmaceutical Sciences, 2019, 09(02), 143-146.
Article DOI: 10.30574/gscbps.2019.9.2.0143
Publication history:
Received on 29 July 2019; revised on 18 August 2019; accepted on 25 November 2019
Abstract:
H. pylori infection is strongly related with chronic gastritis of the stomach, which causes impairment in gastric acid and secretion of pepsin, and linked to male absorption of food-vitamin B12. The most important virulence genes accompanying stomach and intestine disease are (cag A and vac A). Aim of the study: To evaluate the rate of gastric ulcer infection with H. pylori and its detect CagA gene in H.pylori isolated from gastritis. Materials and Methods: A total of 200 biopsy patients aged from (10- ≥ 60) years were collected from Baqubah teaching hospitals. They were suffering from gastric upset and attended to endoscopic unit of department of medicine. Questioners including, sex, age, smoking, presence of cancer, and biopsies of gastric tissue were collected from the corpus or the ant rum or corpus and ant rum of the patient's stomach. Three biopsies were taken from each patient. Histopathologic study, gram staining, and rapid urease test working for each patients. Serology Test Serum Enzyme-Linked Immunosorbent Assay Testing (ELISA).
Keywords:
Gastric ulcer; H. pylori; Cag A gene; Stomach ulcer; Duodenal ulcer
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Copyright © 2019 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
