Conductometric studies of 1, 3, 5 –triazinothiocarbamide at different concentration and temperature

DD Sonone, ME Shelke *, DT Tayade

Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati, Maharashtra, India.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2021, 16(02), 151-154.
Article DOI: 10.30574/gscbps.2021.16.2.0244
Publication history: 
Received on 15 July 2021; revised on 18 August 2021; accepted on 20 August 2021
 
Abstract: 
Conductivity plays vital role in drug diffusion. Thermodynamic parameters affected by substituents of drug. Thermodynamic parameters of 1, 3, 5 –triazinothiocarbamide (1a) have been investigated by using conductometrically carried out at different molar concentrations. This work highlights investigation of G, K and µ values. The thermodynamic parameters viz. ΔH, ΔS and ∆G for ion pair formation determine from the value of ion association constant. This technique is suitable and accurate to study of pharmokinetics and pharmodynamics parameters.
 
Keywords: 
Conductometric measurements; Thermodynamic parameters; Pharmokinetics; Pharmodynamics; S-triazines
 
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