A comprehensive review on spanules: A novel drug delivery system
Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India.
Review Article
GSC Biological and Pharmaceutical Sciences, 2022, 18(01), 100–106.
Article DOI: 10.30574/gscbps.2022.18.1.0372
Publication history:
Received on 29 November 2021; revised on 18 January 2022; accepted on 20 January 2022
Abstract:
Spanules are considered one of the most advantageous drug delivery systems. Multi-drug regimen is the key benefit of Spanules (capsules having granules.) Spanules are constructed for the release of API (Drug) at different rates and times. The first immediate /slow-release pattern gives an initial drug release which is followed by drug release at a constant rate for an extended time.This will result in constantdrugsbeing available for a long time of period. This doses form is useful to overcome repeated drug dosing.
Keywords:
Spanules; Hard gelatin capsule; Immediate drug release; Novel drug delivery system
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