Antibacterial properties of alcohol and water extracts of Waltheria indica (L.) plants collected from Binh Thuan province, Vietnam

Simphathai Mahaxay 1, Dang Thi Ngoc Thanh 2, *, Nguyen Quoc Vu 2, Nguyen Thai Minh Chau 2 and Pham Van Ngot 3

1 Talent Friendship Champasak-Lamdong High School, No. 38 Road, Paksé, Champasak, Laos.
2 Faculty of Natural Science Pedagogy, Sai Gon University, 273 A Duong Vuong Street, Ward 3, District 5, Ho Chi Minh City, Vietnam.
3 Faculty of Biology, HCMC University of Education, 280 A Duong Vuong Street, Ward 4, District 5, Ho Chi Minh City, Vietnam.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2022, 19(02), 137–144.
Article DOI: 10.30574/gscbps.2022.19.2.0160
Publication history: 
Received on 20 March 2022; revised on 26 April 2022; accepted on 28 April 2022
 
Abstract: 
This study aimed to investigate the antibacterial ability of Waltheria indica species collected from two communes of Phan Thiet city, Binh Thuan province. Research methods included making ethanol extracts and decoction and investigating their ability to inhibit bacteria through agar well diffusion method and determining the minimum inhibitory concentration (MIC). The results showed that the ethanol extract was resistant to 5 tested strains of bacteria (Bacillus cereus, Staphylococcus aureus, Enterococcus faecium, Pseudomonas aeruginosa, Escherichia coli) with diameters of bacterial inhibition zones ranging from 6.76 to 14.50 mm, in which the resistance to Gram-positive strains was better than Gram-negative strains. The decoction inhibited only 3/5 of the tested bacterial strains (S. aureus, E. faecium, E. coli) with MICs from 125 to 750 mg/mL (dry weight of plant per volume of decoction). The antibacterial activities of extracts from the stems, leaves, and roots of the plants were different. Samples obtained from the 2 sites also showed different antibacterial capacities.
 
Keywords: 
Bacterial inhibition zone; Binh Thuan; Decoction; Ethanol extract; Minimum Inhibitory Concentration; Waltheria indica
 
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