Liposomes as a novel drug delivery system
HSBPVT'S GOI, Faculty of Pharmacy, Kashti, Ahmednagar, India.
Review Article
GSC Biological and Pharmaceutical Sciences, 2022, 20(03), 336–343.
Article DOI: 10.30574/gscbps.2022.20.3.0372
Publication history:
Received on 20 August 2022; revised on 23 September 2022; accepted on 25 September 2022
Abstract:
Liposome is a microparticulate colloidal vesicle, in which aqueous medium is surrounded by single or multiple concentric layers of phospholipids. Both hydrophilic & hydrophobic drug can be incorporated, water soluble drug being trapped in aqueous core and fat soluble drug in phospholipids. It offers controlled release, targeted drug delivery thus enhanced therapeutic efficacy and reduced dosing frequency. Several liposome based drug formulation are approved for clinical use and many are under extensive investigation. Therapeutically, these are used as carrier for drugs, viruses, bacteria, antigen, peptides (antibiotic), vaccines, genes and diagnostic agents. This review discusses about the method of production and extensive therapeutic potential of liposomes as carriers for targeted and controlled delivery.
Keywords:
Liposomes; Novel drug; Controlled release; Currier; Drug targeting
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Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
