Antioxidant activity of hydroalcoholic extract of leaves of Calotropis procera

Ashish Dixit 1, *, Vibhu Sahani 2, Anil Kumar khareya 3 and Vivek Tiwari 4

1 Spectrum Hi Pharmacy College, Sultanpur, Uttar Pradesh, India.
2 LLRM Medical College, Meerut, Uttar Pradesh, India.
3 Kunwar Harvansh Singh College of Pharmacy, Jaunpur (U.P), India.
4 Ramdham Mahavidhyalaya (Pharmacy), Mau Uttar Pradesh, India.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 22(01), 072-075.
Article DOI: 10.30574/gscbps.2023.22.1.0011
Publication history: 
Received on 01 December 2022; revised on 05 January 2023; accepted on 08 January 2023
 
Abstract: 
Plants are reported to have anticancer, antimicrobial, anti-diabetic, anti-inflammatory and antioxidant properties. In the present study, hydroalcoholic extract of Calotropis gigantea was investigated for its antioxidant activity. Antioxidant activity was determined in vitro by reducing power, DPPH and nitric oxide method. Hydroalcoholic extract of Calotropis procera shown significant antioxidant activity. Calotropis procera (Asclepiadaceae) commonly known as akado and wild growing tropical plant, which possesses number of medicinal properties. It is reported to contain cardiac glycosides, β-sitosterol, madrine, saponins, alkaloids, tannins, trisecharoides and flavonols. The plant has been used for various disease conditions, including leprosy, ulcers, tumours and piles. Various pharmacological activities reported like antifertility, anti-inflammatory activity, hepatoprotective activity, antimyocardial infraction activity and antidiarrhoeal activity.
 
Keywords: 
Calotropis procera; Antioxidant activity; Crude extract; Disc diffusion method
 
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