Analysis of the species composition of the intestinal micro biota in stroke patients: Discovering a new risk factors and screening approaches

Christiyan Kirilov Naydenov 1, * and Ivan Stanchev Mindov 2

1 Department of Neurology and psychiatry at Trakia University, Armeyska 11 str., Stara Zagora city 6000, Bulgaria.
2 Section of Neurosurgery at Trakia University, Armeyska 11 str., Stara Zagora city 6000, Bulgaria.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2023, 23(01), 113–116.
Article DOI: 10.30574/gscbps.2023.23.1.0148
Publication history: 
Received on 25 February 2023; revised on 09 April 2023; accepted on 12 April 2023
 
Abstract: 
The human gut contains microbiota, which refers to the collection of microorganisms that inhabit the body. These gut microorganisms can affect the nervous system through the bidirectional communication between the gut and the brain, known as the gut-brain axis. The microbiota can produce various neurotransmitters and signaling molecules that influence the nervous system and the immune system. Alterations in the composition of the gut microbiota, known as dysbiosis, have been associated with neurological disorders such as Parkinson's disease, Alzheimer's disease, and autism spectrum disorders. Maintaining a good and diverse gut microbiota is important for overall health and wellbeing. The composition of the gut microbiota in stroke patients can differ from that of healthy individuals. The emerging evidence suggests that the gut microbiota may play a role in the pathogenesis of stroke and could potentially be a target for therapeutic and preventing interventions. Research is ongoing to fully understand the changes in gut microbiota composition following stroke. Stroke patients have lower levels of beneficial bacterial species, such as Bifidobacterium spp. and Lactobacillus spp., and higher levels of opportunistic bacteria, such as Enterobacteriaceae and Streptococcus spp. The composition of the gut microbiota can differ depending on the type and severity of stroke.
 
Keywords: 
Nervous system; Bidirectional communication; Gut-brain axis; Stroke; Gut microbiota composition; Risk factors; Stroke screening
 
Full text article in PDF: 
Share this