Tangeretin-a special polymethoxyflavones: An insight into its pharmacological and therapeutic effects on diabetes
1 Department of Biochemistry, North Eastern Hill University, Shillong-793022, Meghalaya, India.
2 Department of Pharmaceutical Science, Dibrugarh University, Dibrugarh-786004, Assam, India.
Review Article
GSC Biological and Pharmaceutical Sciences, 2023, 23(01), 127–136.
Article DOI: 10.30574/gscbps.2023.23.1.0151
Publication history:
Received on 27 February 2023; revised on 09 April 2023; accepted on 12 April 2023
Abstract:
With global diabetes complication growing rapidly at an alarming rate each year, there is an increasing need to find suitable therapeutics for its management, regulation, and treatment which is cost-effective, safe, and naturally available. Continued dependence only on the available synthetic drug is not a solution. Therefore, there is a need to find suitable natural adjuncts to help manage diabetes. Flavonoids are a class of compounds that have been utilized for therapeutic purposes for generations due to their wide and varied pharmacological properties. One such important naturally available flavonoid is tangeretin belonging to a special class of methylated flavonoids found mostly only in citrus fruits. It is reported to possess a lot of pharmaceutic activities, and thus in this brief review, we elucidate its specific importance in the attenuation of diabetic and diabetes-related complications to get a better understanding of its physiological mechanism of action in the context relating to diabetes.
Keywords:
Diabetes; Flavonoid; Natural Product; Tangeretin; Polymethoxyflavones; Therapeutics
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0
