Frequency of hepatitis and HIV co-infection markers in blood donors at the Hospital Professor Bocar Sidy Sall of Kati-Mali

Sanou-Makan Konaté 1, 5, *, Kassoum Kayantao 3, Seydou Simbo Diakité 1, Rokia Diarra 1, Sékou Oumar Coulibaly 2, Almoustapha Ouattara 1, Dida Oumar Diarra 1, Moussa Dembelé 1, Oumar Marico 1, Boucary Ouologuem 1, Binta Djimdé 4, Moussa Djimdé 3 and Alpha Seydou Yaro 3, 5

1 Laboratoire du Centre Hospitalier Universitaire Pr Bocar Sidy Sall de Kati (CHU Kati) Mali
2 Centre National de Transfusion Sanguine (CNTS) Bamako Mali,
3 Malaria Research and Training Center, International Center for Excellence in Research (MRTC, ICER-Mali).
4 Institut National de Santé Publique (INSP); Mali.
5 Laboratoire d’entomologie Parasitologie (LEP), Faculté des Sciences et Techniques (FST), Université des Sciences, des Techniques et des Technologies de Bamako (USTTB); Mali.
 
Research Article
GSC Biological and Pharmaceutical Sciences, 2023, 23(02), 189–196.
Article DOI: 10.30574/gscbps.2023.23.2.0214
Publication history: 
Received on 17 April 2023; revised on 29 May 2023; accepted on 31 May 2023
 
Abstract: 
The transmission of infectious agents such as human immunodeficiency virus (HIV), hepatitis B (HBV), and hepatitis C (HCV) represents the greatest threat to the safety of blood transfusion to the recipient. The association of HIV infection with HBV and/or HCV is common worldwide, due to shared modes of transmission. The prevalence of HIV-HBV co-infection is estimated to be 5-10% in the United States and 20-30% in Asia and parts of sub-Saharan Africa. Other studies report HCV co-infection in 9-25% of HIV-infected patients.
The aim of this study was to determine the frequency of markers of co-infection between hepatitis (B,C) and human immunodeficiency virus in blood donations collected at the CHU Kati blood transfusion center. It was a retrospective study conducted from October 1 to December 31, 2018. Data were collected from blood donors aged 18 to 60 years. The Pre-donation medical interview was the first barrier for the selection of subjects at risk. The sample was composed of 92% males and 8% females out of a total of 507 individuals sampled. Biological screening was performed by ELISA (Enzyme Linked Immuno Sorbent Assay). The results revealed a prevalence of 0.86% of HIV-HBV co-infection only in rhesus negative donors. No co-infection between HIV and HCV was found. This study showed that at the Kati University Hospital, only rhesus-negative donors presented cases of HIV-HBV co-infection.
 
Keywords: 
Co-infection; HIV; HBS; HCV; Blood donors; Mali
 
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Copyright information: 
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

 

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