Pharmaceutical study of Vasa (Adhatoda vasica Linn.) With special reference to its different dosage forms

Aditi R. Shinde *, Bharat J. Rathi and Manasi D. Chunchuwar

Department of Rasa Shastra and Bhaishajya Kalpana. Mahatma Gandhi Ayurved College, Hospital and Research Center Salod (H), Wardha, Maharashtra, India. 
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2023, 23(03), 009–018.
Article DOI: 10.30574/gscbps.2023.23.3.0197
Publication history: 
Received on 09 April 2023; revised on 20 May 2023; accepted on 23 May 2023
 
Abstract: 
Introduction: Adhatoda vasica Linn., a significant quinazoline alkaloid found in the neighboring plant linn, is the source of the drug bromhexine. The Sanskrit phrase "namoolam anaushadham" comes to mind. However, it describes pharmacological activity rather differently from other modern disciplines. Sometimes the Ayurvedic indication for a plant corresponds to the current medical indication for that plant's metabolite or derivatives of metabolites. But frequently, it indicates something that cannot be explained by an active principle. Investigating a medicinal plant's many applications can serve as a foundation for a deeper knowledge of that plant.
Aim: This review is a sincere attempt to cover the many aspects of Vasa. The outcome of this study is intended to add a new stage to the process of creating preparations that contain vasa.
Material and Method: For the current review, Bhaishajya kalpana texts, E-books, research journals, and dissertations were searched, and the data was collected and merged. Vasa is used as a primary medication as well as a major component in a variety of formulations.
Result and Discussion: On search vasa is formulations are found in various dosage forms either as primary medication or compound preparation like swarasa, kalka, kwath, ghrita, taila, asava – arishta, granules, modak, guggulu, khanda are included in present review. All dosage forms all useful in various disease conditions according to vaya, kala, prakriti etc. It is a substance that has attracted notice due to its usage in many kalpanas, and virtually every kalpana of this medication is present in classics of ancient literature that draws attention to its utility in various kalpanas. 
 
Keywords: 
Vasa; Dosage form; Vasavaleha; Panchavidha kashay kalpana; Modified dosage form; Vasa ghrita
 
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