A review on recent advantages and evaluation of microparticles and their applications

Vinayak A. Katekar 1, Prafful P. Kothari 2, *, Aarti A. Nahar 3, Pooja A. Salve 4, Harsha H. Shendurkar 5 and Shruti A. Adhau 6

1 Department of Quality Assurance, Shraddha Institute of Pharmacy, Washim, Maharastra, India.
2 Department of Pharmaceutics, Pataldhamal Wadhwani College of Pharmacy, Yavatmal, Maharashtra, India.
3 Department of Pharmaceutical Technology (Biotechnology), National Institute of Pharmaceutical Education and Research, S. A. S. Nagar, Punjab, India.
4 Department of Quality Assurance, Rajarshi Shahu College of Pharmacy, Buldhana, Maharastra, India.
5 Department of Quality Assurance Smt. kishoritai bhoyar college of pharmacy, Nagpur, Maharastra, India.
6 Department of Pharmaceutics, Vidybharti College of Pharmacy, Amravati, Maharastra, India.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2023, 24(02), 297–307.
Article DOI: 10.30574/gscbps.2023.24.2.0320
Publication history: 
Received on 29 June 2023; revised on 20 August 2023; accepted on 22 August 2023
 
Abstract: 
Microparticles are free spherical dust between 1 and 1000 microns made of synthetic, non-biodegradable, and non-biodegradable polymers. There are two types of microparticles: microcapsules and micro matrix. The main types of microparticles are magnetic microparticles, polymer microparticles, bio-adhesive microparticles, biodegradable polymer microparticles, synthetic polymer microparticles, floating microparticles, and radioactive microparticles. The advantage of microcarriers over nanoparticles is that they do not cross the 100 nm interstitium during lymphatic transport and therefore act locally. Toxic substances can be solidified in the form of micro-encapsulated and dried particles. Moreover, methods to characterize numerous physicochemical parameters like drug release, thermal properties, and particle size are introduced, along with new tests like in vitro leaching tests and floating tests.
 
Keywords: 
Microparticles; Micrometrics; Polymer; Antibiotic; Microcapsules; Applications of microparticles
 
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