The prevalence of typhoid fever in Bingham University
DOI:
https://doi.org/10.30574/gscbps.2017.1.3.0052Keywords:
Prevalence, Salmonella typhi, Widal test, Stool cultureAbstract
Typhoid fever remains a major cause of enteric disease and a significant public health problem. The disease is said to be very prevalent in the developing countries, of which Nigeria is one. The aim of this study is to determine the prevalence of typhoid fever among Bingham University students. A total of 125 blood and stool samples were collected randomly from both male and female students of Bingham University. The blood samples were tested for salmonella antigen using Widal test while stool samples were cultured on Salmonella/Shigella agar for the isolation of the causative agent. From the Widal test 80 (69.6%) samples were positive for Salmonella typhi infection, while the stool culture yielded 94 (75.2%) samples that showed the presence of Salmonella typhi. The gender distribution showed that the prevalence was higher in female students (87.30%) than the male students (62.90%). The infection was highest in the age group of 21-25 years which had 86.36% prevalence. The lowest prevalence was observed in the age group 26-30 years with 46.15%. The prevalence of typhoid fever is generally high in the University. Therefore, proper sanitary measures should be observed by the students in the university. The results also proved the superiority and reliability of stool culture technique over the Widal test in the diagnosis of Salmonella typhi infection. This study will provide the school administration adequate knowledge on the infection and serve as a guide in proffering solution to halt further spread of the disease in the institution.Metrics
References
Chin J. (2000). Control of communicable disease manual. American Public Health Association, 17.
Buckle GC, Fischer Walker CL and Black RE. (2012). Typhoid fever and Paratyphoid fever: systematic review to estimate global morbidity and mortality for 2010. Journal of global Health, 2(1), 2.
Humphrey T. (2004).Salmonella, stress responses and food safety. Nature Reviews Microbiology, 2, 504-509.
Crump J, Youssef FG, Luby SP, Wasfy MO, Rangel JM, Taalat M, Oun SA and Mahoney FJ. (2004). Estimating the incidence of typhoid fever and other febrile illnesses in developing countries. Emerging infectious diseases, 9(5), 539.
Den W, Shian-Ren L, Plunkett G, Mayhew GF, Rose DJ, Burland V, Kodoyianni V, Schwartz DC and Blattner, FR. (2003). Comparative Genomics of Salmonella enteric serovar Typhi Strains Ty2 and CT18. Journal of Bacteriology, 185, 2330-2337.
Hatta M, Gorris MG, Heerkens E, Gooskens J and Smits, HL. (2002). Simple dipstick assay for the detection of Salmonella typhi- specific IgM antibodies and the evolution of the immune response in patients with typhoid fever. American Journal of Tropical Medicine and Hygiene, 66, 416-421.
Melzer M, Altman G, Rakowszcyk M, Yosipovitch ZH and Barsilai B. (2004). Salmonella infections of the kidney.The Journal of urology 94, 23–27.
Lynch MF, Blanton EM, Bulens S, Polyak C, Vojdani J and Stevenson J. (2009). Typhoid fever in the United States, 1999–2006. The Journal of the American Medical Association, 302(8), 59–65.
Marks F, Von Kalckreuth V and Aaby P. (2017). Incidence of invasive Salmonella disease in sub-Saharan Africa: a multicentre population-based surveillance study. The Lancet Global Health, 5(3), e310-e323.
Philippa MA, Shanahan J, Mary V, Thomson CJ and Sebastian GB. (2003). Molecular analysis of and identification of antibiotic resistance genes in clinical isolates of Salmonella typhi from India. American Society for Microbiology, 36, 1595.
Agwu E, Ihongbe JC, Okogun GR and Inyang NJ. (2009). High incidence of co-infection with malaria and typhoid in febrile HIV infected and AIDS patients in Ekpoma, Edo state, Nigeria. Brazilian Journal of Microbiology, 40, 329- 332.
Crump JA and Mintz ED. (2010). Global Trends in Typhoid and Paratyphoid Fever. Clinical Infectious Diseases, 50(2), 241-246.
Parry CM (2005) Epidemiological and clinical aspects of human typhoid fever: In, Salmonella infections: clinical, immunological and molecular aspects, Mastroeni, P andMaskell, D. (ed), University Press, Cambridge, 1-10.
Cheesbrough M. (2005). District laboratory practice in tropical countries part 2 (2nd Edition), Cambridge University Press, UK, 240 - 243.
Udeze AO, Abdulrahman F, Okonko IO and Anibijuwon II. (2010). Seroprevalence of Salmonella typhi and Salmonella paratyphi among the first year students of University of Ilorin, Ilorin, Nigeria. Middle-East Journal of Scientific Research, 6 (3), 257-262.
Ajibade VA. (2013). Prevalence of resistance among Salmonella typhi isolates in Ekiti State, Southwestern Nigeria 2009-2011. Global Journal of Medical Research Microbiology and Pathology, 13(3), 4-8.
Uttah EC, Osim SE, Etta H, Ogban E and Okon NEE (2000). Four-year longitudinal assessment of the prevalence of typhoid fever among those attending the General Hospital Etinan, Nigeria. International Journal of Scientific and Research Publications, 3 (7), 150.
Emmanuel IU (2017). Sero-prevalence of Salmonella typhi antibodies among adult residents of some selected rural communities of Abia and Enugu States, Southeast Nigeria: a cross-sectional study. International Journal of Research in Medical Sciences. 5(8), 3400-340.
Okonko IO, Soleye FA, Eyarefe OD, Amuson TA, Abubakar MJ, Adeyi AO, OjezeleMO and Fadeyi A. (2010). Prevalence of Salmonella typhi among patients in Abeokuta South-Western Nigeria. British Journal of Pharmacology and Toxicology, 1(1), 6-14.
Eze EA, Ukwah BN, Okafor PC and Ugwu KO. (2011). Prevalence of Malaria and typhoid co-infections in University of Nigeria, Nsukka District of Enugu State, Nigeria. African Journal of Biotechnology, 10(11), 2135-2143.
Zailani SB, Aboderin AD and Onipede AD. (2004) Effect of socioeconomic status, age and sex on antibody titer profile to Salmonella typhi/paratyphi in Ile-Ife, Nigeria. Nigerian journal of medicine: journal of the National Association of Resident Doctors of Nigeria, 13(4), 383-387.
Onabowale O and Ogunbiyi TA. (1996). Typhoid enteritis in Lagos, Nigeria. Nigerian Medical Journal, 6(4), 45-47.
Kabiru OA, Yetunde OO, Oladeji GO and Akitoye OC. (2012). A retrospective study of community acquired Salmonella infections in patients attending public hospitals in Lagos, Nigeria. Journal of Infection in Developing Countries, 5(6), 387-395.
AjayiOE, Olukunle OF and Boboye BE. (2015). Prevalence of Typhoid Fever among Different Socio- demographic Groups in Ondo State, Nigeria. Journal of Applied Life Sciences International, 3(2), 89-95.
Mastroeni P and Maskell D. (2005). Epidemiological and Clinical aspects of human typhoid fever. Salmonella infections: Clinical, Immunological and Molecular Aspects, University Press, Cambridge, 1-10.
Parry CM. (2006). Epidemiological and clinical aspects of human typhoid fever. In: Matroeni, P. and Maskell, D. (Eds.) Salmonella infections: clinical, immunological and molecular aspects, University Press, Cambridge, 1-18.
Nsutebu EF and Ndumbe PM (2001). The Widal test for typhoid fever: is it useful? Africa Health, 23(3), 5-8.
Aziz Tand Haque SS. (2012). Role of Widal test in the diagnosis of typhoid fever in context to other test. American Journal of Biochemistry, 2(1), 16-18.
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