Occupational exposure to petroleum products and its effects on heavy metal metabolism in automobile mechanics

Ayobola Abolape Iyanda

doi:10.30574/gscbps.2019.6.1.0164

Authors

Ayobola Abolape Iyanda Department of Chemical Pathology, College of Health Sciences, Ladoke Akintola University of Technology, Osogbo, Nigeria.

DOI:

https://doi.org/10.30574/gscbps.2019.6.1.0164

Keywords:

Auto- mechanics, Heavy metals, Petroleum products, Skin

Abstract

In fuel filling station attendants various pathological events have been linked with exposure to petroleum products, with the severity of these events correlated with blood levels of benzene, toluene, ethylbenzene and xylene (BTEX). BTEX are volatile compounds, so exposure through the nasal route is possible yet in auto-mechanics because dermal exposure is also pronounced, this may lead to the presence of non-volatile petroleum product constituents (e.g. heavy metals) in their systemic. The aim of the study is estimate heavy metal levels in serum of auto-mechanics. Random sampling technique was employed to recruit participating age-matched control and auto-mechanics. Questionnaire was administered, with focus on demographic- age, lifestyle, work experience in years, and work hours, and the type of protective gear used during work hours. Serum obtained from 5 mL of venous blood was used to estimate levels of lead, aluminium, nickel, silicon, cadmium, and arsenic by atomic absorption spectrometry. Student’s t-test was used to determine statistical difference between the means of both groups, p ≤ 0.05 was considered significant. The duration of exposure in years was 6- 9 (range) and work-hours (automobile mechanics) per day was an average of 8 hours. All the heavy metals estimated were significantly higher in automobile mechanics compared with control subjects. There are indications that elevated levels of lead, aluminium, nickel, silicon, cadmium, and arsenic is associated with this occupation.

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References

Kamal A, Cincinelli A, Martellini T, Palchetti I, Bettazzi F andMalik RN. (2015). Health and carcinogenic risk evaluation for cohorts exposed to PAHs in petrochemical workplaces in Rawalpindi city (Pakistan). International Journal of Environmental Health Research, 5, 1-21.

Onunkwor B, Dosumu O, Odukoya OO, Arowolo T andAdemuyiwa O. (2004). Biomarkers of lead exposure in petrol station attendants and auto-mechanics in Abeokuta, Nigeria: effect of 2-week ascorbic acid supplementation. Environmeental Toxicology and Pharmacology, 17(3), 169-76.

Osuji LC, Onojake CM. 2004. Trace heavy metals associated with crude oil: a case study of Ebocha-8 oil-spill-polluted site in Niger Delta, Nigeria. Chemistry and Biodiversity, 1(11), 1708-15.

Chen F, Jiang S. 2009. Determination of Hg and Pb in fuels by inductively coupled plasma mass spectrometry using flow injection chemical vapour generation. Analytical Sciences, 25, 1471-6.

Al-Ghouti MA, Al-Atoum L. 2009. Virgin and recycled engine oil differentiation: a spectroscopic study. Journal of Environmental Management, 90(1), 187-95.

Kim Y, Kim NY, Park SY, Lee DK, Lee JH. 2013. Classification and individualization of used engine oils using elemental composition and discriminant analysis. Forensic Science International, 230(1-3), 58-67.

Iyanda AA. 2014. Kerosene: A study of serum levels of select heavy metals and histology of brain, lung, heart and ileum of rats chronically exposed. British Journal of Pharmaceutical Research, 4(6), 731-738.

Poet TS, McDougal JN. 2002. Skin absorption and human risk assessment. Chemico-Biological Interaction, 140, 19–34.

Wester RC, Maibach HI. (1993). Animal models for percutaneous absorption, in Wang RGM, Knaak JB, Maibach HI (eds.): Health Risk Assessment— Dermal and Inhalation Exposure and Absorption of Toxicants. Boca Raton: CRC Press, 89–103.

Ross JH, Driver JH, Harris SA, Maibach HI. 2005. Dermal absorption of 2, 4-D: A review of species differences. Regulatory Toxicology and Pharmacology, 41, 82–91.

Rice RH, Mauro TM. 2008. Toxic responses of the skin. In Casserret and Doull’s Toxicology the basic science of poisons. Editor CD Klaassen. 7th edition, pg 741-760.

Iyanda AA, Iheakanwa CI. 2018. Evaluation of heavy metal levels in serum of wistar rats exposed to engine oil. Progress in Health Sciences, (in print).

Tunsaringkarn T, Siriwong W, Rungsiyothin A, Nopparatbundit S. 2012. Occupational Exposure of Gasoline Station Workers to BTEX Compounds in Bangkok, Thailand. The International Journal of Occupational and Environmental Medicine, 3, 117-25.

Iyanda AA, Anetor JI, Adeniyi FAA. 2011. Altered copper level and renal dysfunction in Nigerian women using skin-whitening agents. Biological Trace Element Research, 143(3), 1264-1270.

Rekhadevi PV, Mahboob M, Rahman MF, Grover P. 2011. Determination of genetic damage and urinary metabolites in fuel filling station attendants. Environmental and Molecular Mutagenesis, 52(4), 310-8.

Villeneuve S, Cyr D, Lynge E. 2010. Occupation and occupational exposure to endocrine disrupting chemicals in male breast cancer: a case-control study in Europe. Occupation and Environmental Medicine, 67(12), 837–844.