Descriptive epidemiology of uterine cervix cancer at the medical oncology unit of the Yaoundé general hospital-Cameroon

Authors

  • Yongsi H. Blaise Nguendo Institute for Training and Demographic Research (IFORD), University of Yaoundé II, Cameroon.
  • Fossi Cedric Tchinda Department of Public Health, School of Health Sciences, Catholic University of Central Africa, Cameroon.

DOI:

https://doi.org/10.30574/gscbps.2019.9.1.0189

Keywords:

Epidemiology, Risks factors, Uterine cervix cancer, Yaoundé General Hospital, Cameroon

Abstract

Uterine cervix cancer is the most common cancer found worldwide, mostly in developing countries. In Africa as well as in the Caribbean, it represents the second cause of mortality, just after maternal mortality. In Cameroon, data on cervix cancer are erratic, whereas the incidence of the disease is increasing. This paper is designed to define the epidemiological features of uterine cervix cancer, since it could help identifying behavioral, environmental and genetic risks factors involved in its development. A 4-year retrospective study of patients seen with the diagnosis of cervix cancer at the Medical Oncology unit of the Yaoundé General Hospital between January 2012 and December 2015. Then a prospective study was conducted among health professionals working in the same oncological unit in 2017. The demographic pattern (age of patients, socio professional activity, marital status), clinical features (cancer diagnosis), treatment modalities and outcome were studied. Of the 7775 patients enrolled in the study, 3.61% (n = 281) were carriers of uterine cervix cancer. We noted a relatively large annual growth of cases and the annual average was 27 cases. The average age of our patients was 55.46 years with extreme ages ranging from 23 to 88 years Carcinoma of the cervix occurs much more frequently among women of lower income and education level. Although several risk factors were suspected in our study such as age, sexual factors (including STIs), none of them really testify their responsibility in the genesis of the cancer. However, improving the effective management of different patients suffering from cervix cancer requires an improvement in the conditions for the early and voluntary detection of people at risk, and the quality of care administered to patients.

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References

Disaia PJ and Creasman WT. (1993). Pre invasive disease of the cervix. Clinical Gynaecologic Oncology, Mosby, 4, 1-36.

Chidyaonga-Maseko F, Chirwa ML and Muula AS. (2015). Underutilization of cervical cancer prevention services in low and middle income countries: A review of contributing factors, The Pan African Medical Journal, 21.

WHO/ICO Information Center of HPV and Cervical Cancer (HPV Information Center). Human Papillomavirus and Related Cancers in the World. Summary Report 2010.

Poorolajal J and Jenabi E. (2016). The association between BMI and cervical cancer risk: A meta-analysis, European Journal of Cancer Prevention, 25(3), 232-238.

Parkin DM, Pisani P and Munoz N. (1998). The global health burden of infection. In: Weiss, R.A., Beral, V., Newton R, editor(s). Infections and human cancer. Cold Spring Harbor Laboratory Press.

Ferlay J, Soerjomataram I, Ervik M and GLOBOCAN. (2012). Cancer Incidence and Mortality Worldwide: IARC Cancer base, 1 (11).

Forouzanfar MH, Foreman KJ and Delossantos AM. (2011). Breast and cervical cancer in 187 countries between 1980 and 2010 : a systematic analysis, Lancet, (11), 61351-61352.

Curado MP, Edwards B, Shin HR, Storm H, Ferlay J, Heanue M, et al. (2007). Cancer incidence in five continents. IARC Scientific publications, Lyon, 9 (160), 23-41.

Momenimovahed Z, Ghoncheh, M, Pakzad R, Hasanpour H and Salehiniya H. (2017). Incidence and mortality of uterine cancer and relationship with Human Development Index in the world, Cukurova Medical Journal, 42, 233-240.

Enow Orock GE, Ndom P and Doh AS. (2012). Current cancer incidence and trends in Yaounde, Cameroon. Oncol Gastroenterol Hepatol., 1(1), 58–63.

Sankaranarayanan R, Basu P, Wesley RS, Mahe C, Keita N, Mbalawa CC, Sharma R, Dolo A, Shastri SS, Nacoulma M, Nayama M, Somanathan T, Lucas E, Muwonge R, Frappart L and Parkin DM. (2010). IARC Multicentre Study Group on Cervical Cancer Early Detection; Accuracy of visual screening for cervical neoplasia: Results from an IARC multicentre study in India and Africa. Int J Cancer. 110(6), 907–913.

Bruni L, Diaz M, Castellsagué M, Ferrer E, Bosch FX and de Sanjosé S. (2010). Cervical human papillomavirus prevalence in 5 continents: Meta-analysis of 1 million women with normal cytological findings, The Journal of Infectious Diseases, 202(12), 1789-1799.

Bello TO, Olugbenga-Bello AI, Oguntola AS, Adeoti ML and Ojemakinde OM. (2012). Knowledge and Practice of Breast Cancer Screening Among Female Nurses and Lay Women in Osogbo, Nigeria, West African Journal of Medicine, 30 (4), 296-300.

WHO. (2010). Le cancer du col de l’utérus dans la région africaine de l’OMS : situation actuelle et perspectives, 6.

Percy C, Van Holten V and Muir C. (1990). International Classification of Diseases for Oncology (ICD-O). 2nd ed. Geneva: WHO.

Pierre A and Bernard-Alex G. (2015). Les cancers dans les pays en développement. Médecine tropicale, 1-7.

Enow Orock GE, Ndom P and Doh AS. (2012). Current cancer incidence and trends in Yaounde, Cameroon. Oncol Gastroenterol Hepatol., 1(1), 58–63.

Tebeu PM, Petignat P and Mhawech-Fauceglia P. (2009). Gynecological malignancies in Maroua, Cameroon, Int J Gynaecol Obstet, 104(2), 148–159.

Makuza JD, Nsanzimana S, Muhimpundu MA, Pace LE, Ntaganira J and Riedel DJ. (2015). Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda. The Pan African Medical Journal, 22, 35-45.

Fitzmaurice C, Dicker D, Pain A, Hamavid H, Moradi-Lakeh M, MacIntyre MF and Wolfe C. (2015). The global burden of cancer. JAMA Oncology, 1(4), 505-527.

Mariko Kadidiatou épouse keita. (2008). Aspects histopathologiques des cancers du col de l’utérus au Mali: à propos de 85 cas. Tthese de Doctorat en médecine, Université de Bamako, 79.

Diabate AS, Gui- Bile LN, Dede NS, Kouadio E, Kabas RM, Yapo P and Ouattara DN. (2015). IRM du cancer du col de l’utérus en milieu tropical, Journal African Imagery Médical, 1(7), 30-38.

Touré M, Adoubi I, Didi-Kouko Coulibaly J, Toowlis A and Echimane KA. (2011). Aspects épidémiologiques, anatomo-cliniques et thérapeutiques du cancer du col utérin dans le service de cancérologie du CHU de Treichville à Abidjan, Médecine d’Afrique Noire, 58(10), 473-478.

Bannour N, Boughizane S, Naifer R, Slama O, Trabelsi A, Bibi M, Zheni S, Ben Abdallah M., Khairi H and Bouaouina N. (2004). Le cancer invasif du col utérin dans le centre tunisien. Approches épidémiologique, clinique et thérapeutique. Étude rétrospective de 96 cas. Oncologie, 6, 481-488.

Ries L, Melbert D, Krapcho M, Mariotto A, Miller BA, Feuer EJ et al. (2007). SEER Cancer Statistics Review, 1975-2004, National Cancer Institute. Bethesda.

Durowade K, Osagbemi G, Salaudeen A, Musa O, Akande T, Babatunde O and Ibrahim O. (2012). Prevalence and risk factors of cervical cancer among women in an urban community of Kwara State, north central Nigeria, Journal of Preventive Medicine and Hygiene, 53, 12-22.

Munoz N and Bosch FX. (1996).The causal link between HPV and cervical cancer and its implications for prevention of cervical cancer, Bull Pan Am Health Organ., 30 (4), 362-77.

Horo A, Jaquet A, Ekouevi D, Toure B, Coffie P, Effi B, Messou E, Minga A, Moh R, Kone M, Dabis F and Sasco Annie J. (2012). Cervical cancer screening by visual inspection in Côte d’Ivoire, operational and clinical aspects according to HIV status, BMC Public Health, 12, 237.

NPB. (2007).

Bannour N, Boughizane S, Naifer R, Slama O, Trabelsi A, Bibi M, Zheni S, Ben Abdallah M., Khairi H and Bouaouina N. (2004). Le cancer invasif du col utérin dans le centre tunisien. Approches épidémiologique, clinique et thérapeutique. Étude rétrospective de 96 cas. Oncologie, 6, 481-488.

Bouslah S, Soltani MS, Ben Salah A and Sriha A. (2014). Connaissances, attitudes et pratiques des femmes tunisiennes en matière de dépistage du cancer du sein et de celui du col de l’utérus, Psycho Oncologie, 8, 123.

Bello TO, Olugbenga-Bello AI, Oguntola AS, Adeoti ML and Ojemakinde OM. (2012). Knowledge and Practice of Breast Cancer Screening Among Female Nurses and Lay Women in Osogbo, Nigeria, West African Journal of Medicine, 30 (4), 296-300.

Kemfang DJ, Ngowa1 LF, Domgue FJ, Ngassam A, Noa CC, Tsuala FJ, Fongang E and Jean Marie Kasia MJ. (2015). Connaissances, attitudes et pratiques des professionnels de la santé sur le cancer du sein à Yaoundé, Health Sciences Diseases, 16(3), 1-6.

Lurie N, Margolis KL, McGovern PG, Mink PJ and Slater JS. (1997). Why do patients of female physicians have higher rates of breast cancer and cervical cancer screening? Journal of General Internal Medecine, 12, 34-43.

Crosbie EJ, Einstein MH, Franceschi S and Kitchener HC. (2013). Human papillomavirus and cervical cancer, Lancet, 382(9895), 889-899.

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Published

2019-10-30

How to Cite

Nguendo, Y. H. B., & Tchinda, . F. C. (2019). Descriptive epidemiology of uterine cervix cancer at the medical oncology unit of the Yaoundé general hospital-Cameroon. GSC Biological and Pharmaceutical Sciences, 9(1), 083–091. https://doi.org/10.30574/gscbps.2019.9.1.0189

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Original Article