Pulsed intense light to treat dry eye syndrome
DOI:
https://doi.org/10.30574/gscbps.2019.9.3.0221Keywords:
Dry eye syndromes, Intense pulsed light therapy, Meibomian glands, Tarsal gland, Phototherapy, Eye diseasesAbstract
Intense Pulsed Light (IPL) is the therapeutic tool implemented in the treatment of dry eye, characterized by the emission of waves of 500-1200nm in the region of the upper and lower eyelids. Dry eye is a recurring complaint in ophthalmology offices and has an impact on the patient's quality of life. It results from dysfunction of the meibomian glands, duct obstruction, and quantitative and qualitative changes in glandular secretion. It is manifested by dryness and irritation, foreign body sensation, burning, tearing, and eye fatigue. The available treatments are short term palliative with unsatisfactory results. To determine through a literature review, the benefit of using intense pulsed light for dry eye treatment. Methodology: We searched the Cochrane database, PubMed, Embase, Scopus, Web of Science, and Google Scholar (gray literature) using the keywords for an independent, blinded, peer-reviewed selection of articles to be met following pre-established criteria. Studies evaluated the use of IPL in patients with dry eye, despite the benefit found, focus on the objective and subjective assessment of the eye more frequently. Evidence-based clinical guidelines are required for the use of intense pulsed light in the treatment of Meibomian Gland Dysfunction (MGD), as well as a device and algorithm for indications of therapeutic use.
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Mejía LF, Gil JC and Jaramillo M. (2019). Terapia de luz pulsada intensa regulada: un tratamiento complementario prometedor para la enfermedad de ojo seco. Archivos de La Sociedad Española de Oftalmología, 94(7), 331-336.
Vegunta S, Patel D and Shen JF. (2016). Combination Therapy of Intense Pulsed Light Therapy and Meibomian Gland Expression (IPL/MGX) Can Improve Dry Eye Symptoms and Meibomian Gland Function in Patients with Refractory Dry Eye. Cornea, 35(3), 318–322.
Dell SJ. (2017). Intense pulsed light for evaporative dry eye disease. Clin Ophthalmol, 20(11), 1167-1173.
Vigo L, Giannaccare G, Sebastiani S, Pellegrini M and Carones F. (2019). Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction. J Vis Exp, 1(146).
Dell SJ, Gaster RN, Barbarino SC and Cunningham DN. (2017). Prospective evaluation of intense pulsed light and meibomian gland expression efficacy on relieving signs and symptoms of dry eye disease due to meibomian gland dysfunction. Clin Ophthalmol, 2(11), 817-827.
Rong B, Tang Y, Tu P, Liu R, Qiao J and Song W. (2018). Intense Pulsed Light Applied Directly on Eyelids Combined with Meibomian Gland Expression to Treat Meibomian Gland Dysfunction. Photomedicine and Laser Surgery, 36(6), 326–332.
Gupta PK, Vora GK, Matossian C, Kim M and Stinnett S. (2016). Outcomes of intense pulsed light therapy for treatment of evaporative dry eye disease. Canadian Journal of Ophthalmology/Journal Canadien d’Ophtalmologie, 51(4), 249–253.
Toyos R, McGill W and Briscoe D. (2015). Intense Pulsed Light Treatment for Dry Eye Disease Due to Meibomian Gland Dysfunction; A 3-Year Retrospective Study. Photomedicine and Laser Surgery, 33(1), 41–46.
Rong B, Tang Y, Liu R, Tu P, Qiao J, Song W and Yan X. (2018). Long-Term Effects of Intense Pulsed Light Combined with Meibomian Gland Expression in the Treatment of Meibomian Gland Dysfunction. Photomed Laser Surg, 36(10), 562-567.
Vora GK and Gupta PK. (2015). Intense pulsed light therapy for the treatment of evaporative dry eye disease. Current Opinion in Ophthalmology, 26(4), 314–318.
Mandal P, Khan MA and Shah S. (2017). Drugs – Do we need them? Applications of non-pharmaceutical therapy in anterior eye disease: A review. Contact Lens and Anterior Eye, 40(6), 360–366.
Albietz JM and Schmid KL. (2017). Intense pulsed light treatment and meibomian gland expression for moderate to advanced meibomian gland dysfunction. Clinical and Experimental Optometry, 101(1), 23–33.
Arita R, Fukuoka S and Morishige N. (2019). Therapeutic efficacy of intense pulsed light in patients with refractory meibomian gland dysfunction. Ocul Surf, 17(1), 104-110.
Seo KY, Kang SM, Ha DY, Chin HS and Jung JW. (2018). Long-term effects of intense pulsed light treatment on the ocular surface in patients with rosacea-associated meibomian gland dysfunction. Cont Lens Anterior Eye, 41, (5), 430-435.
Guilloto SC, García JLM and Colmenero ER. (2017). Efecto del láser de luz pulsada en pacientes con síndrome de ojo seco. Archivos de La Sociedad Española de Oftalmología, 92(11), 509–515.
Li D, Lin S and Cheng B. (2019). Intense Pulsed Light Treatment for Meibomian Gland Dysfunction in Skin Types III/IV. Photobiomodulation, Photomedicine, and Laser Surgery, 37(2), 70–76.
Karaca EE, Evren Kemer Ö and Özek D. (2018). Intense regulated pulse light for the meibomian gland dysfunction. Eur J Ophthalmol, 4, 1120672118817687.
Al-Saedi Z, Zimmerman A, Bachu RD, Dey S, Shah Z and Baugh R. (2016). Dry Eye Disease: Present Challenges in the Management and Future Trends, 22(28), 4470-4490.
Liu R, Rong B, Tu P, Tang Y, Song W and Toyos R. (2017). Analysis of Cytokine Levels in Tears and Clinical Correlations After Intense Pulsed Light Treating Meibomian Gland Dysfunction. Am J Ophthalmol, 183, 81- 90.
Song WJ and Yan XM. (2018). Research progress of intense pulsed light treatment on meibomian gland dysfunction and relevant dry eye diseases. Europe PMC, 54(2), 140-143.
Craig JP, Chen YH and Turnbull PRK. (2015). Prospective Trial of Intense Pulsed Light for the Treatment of Meibomian Gland Dysfunction. Investigative Opthalmology & Visual Science, 56(3), 1-14.
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