Biochemical profiling of different extracts of Centratherium anthelminticum seeds and its synergistic, antimicrobial activity on clinical, drug resistant and standard strains of some common microorganisms

Authors

  • KM Thara Department of Biotechnology, University of Calicut, Thenjippalam, Malappuram District, Kerala, India, Pin-673635.

DOI:

https://doi.org/10.30574/gscbps.2020.10.1.0009

Keywords:

Antimicrobial activity, MRSA, HPLC, Centratherumanthelminticum, Biochemical profiling

Abstract

Extracts of seeds of Centratherium anthelminticum was prepared by Bioassay guided fractionation using different solvents. Different extracts from the plant Centratherium anthelminticumwas biochemically analyzed for different bioactive components and properties. It shows an inhibitory action on different clinical strains within a range of 100 -500µg/ ml.

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References

Ann MB andZigang D. (2011).2- Epigallocatechin 3-Gallate and Green Tea Catechins: United They Work, Divided They Fail.,Cancer Prev Res, 8(2), 514-519.

Thara KM, Zuhara KF and Raji TK. (2013). Inhibitory and synergistic effect of Pterocarpusmarsupeum extracts on clinical and standard strains of microorganisms and its biochemical analysis. Indo american journal of pharmaceutical research. Indo American Journal of Pharm Research, 3, 5583-5593.

Harborne JB. (1989). Methods in plant biochemistry, In: Plant phenolics: Academic Press, London, UK.

Kessler MU and Jung L. (2003). Anti prooxidant activity of rutin and quercetinderivatives.J.Pharm.Pharmacol, 55(4), 131-142.

Mahesh B and Satish S. (2008). Antimicrobial Activity of Some Important Medicinal Plant Against Plant and Human Pathogens. World Journal of Agricultural Sciences, 4, 839-843.

McDonald S, Prenzler PD, Autolovich M and Robards K. (2001). Phenolic content and antioxidant activity of olive extracts. Food Chemistry, 73(5), 73-84.

Singleton VL, Orthofer R and Lamuela-Raventos RM. (1999). Analysis of total phenols andother oxidation substrates and antioxidants bymeans of Folin-Ciocalteau reagent. Methods Enzymol, 299, 152-178.

Bauer AW, Kirby WMM, Sherris JC and Turk M. (1966). Antibiotic susceptibility testing by a standardized single disc method. Am J ClinPathol, 45(8), 493–496.

Kamicker BJ, Michael TS, Frank K. Fadia DH, Wenchi S, Kim C, Joan D and Thomas DG. (2008). Bacterial Efflux Pump Inhibitors. From: Methods in Molecular Medicine, Vol. 142: New Antibiotic Targets, Edited by: W. Scott Champney © Humana Press Inc., Totowa, NJ.

Masoodi MH, Bahar A, Iqbal MZ, Saroor AK, Shamshir K and Singh P. (2008). Antibacterial activity of whole plant extract of Marrubiumvulgare. African Journal of Biotechnology, 7(2), 86-87.

Parekh J, Karathia N and Chanda S. (2006). Screening of some traditionally used medicinal plants for potential antibacterial activity. Indian Journal of Pharmaceutical Science, 68(6), 832-834.

Patel S, Shah, RS and Goyal R. (2006). Antihyperglycemic, antihyperlipidemicand antioxidant effects of Dihar, a polyherbal ayurvedic formulation in streptozotocin induced diabetic rats. Indian Journal of Experimental Biology, 47, 35-39.

Siwaporn P, Michael J, Mulvany Y, AllenbachV, Andrew M, Kurt H, Poungpen S and Chaweewan J. (2011). Effects of an n-butanol extract from the stem of Tinosporacrispa on blood pressure and heart rate in anesthetize ratsJournal of Ethnopharmacology, 133, 675-686.

Swami S, Raja Chakraborty C, Sridhar YSR and Biplab D. (2010). Free radicals, antioxidants, diseases and phytomedicines: current status and future prospect international journal of Pharmaceutical Sciences Review and Research, 3, 235-240.

Khare C. (2007).Centratherumanthelminticum Kuntze. In: Khare C. (eds) Indian Medicinal Plants. Springer, New York, NY.

ToobaLateef, Shamim A and QureshN.(2016).Centratherumanthelminticum and Withaniacoagulans Improves Lipid Profile and Oxidative Stress in Triton X-100 induced Hyperlipidemic Rabbits, International Journal of Pharmacognosy and Phytochemical Research, 8(6).

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Published

2020-01-30

How to Cite

Thara, . K. (2020). Biochemical profiling of different extracts of Centratherium anthelminticum seeds and its synergistic, antimicrobial activity on clinical, drug resistant and standard strains of some common microorganisms. GSC Biological and Pharmaceutical Sciences, 10(1), 118–125. https://doi.org/10.30574/gscbps.2020.10.1.0009

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Original Article