Bioactivities of forest medicinal plants on kutai ethnic (Indonesia) of tapak leman (Hippobroma longiflora (L) G. Don)
DOI:
https://doi.org/10.30574/gscbps.2020.11.2.0125Keywords:
Phytochemical, Toxicity, Antioxidant, AntibacterialAbstract
Indonesian forests are one of the richest ecosystems in the world. Secondary metabolites with molecular structures and various biological activities of medicinal plant extracts have excellent potential to be developed into medicines of various diseases. Phenolic compounds found in plants have many biological effects including antioxidants and antimicrobials. Secondary metabolite compounds play a protective role against damage caused by disease. Traditional medicine and treatment among the people of Kutai Kartanegara is very diverse and has been widely used. Type of Tapak Leman (Hippobroma longiflora (L) G. Don) is one type of forest plants have been used as a medicinal plant by Ethnic Kutai with the efficacy of treatment of kidney stones and increase of stamina or vitality. The aim of study is to investigate the biological activity of Tapak Leman forest type that had been used as medicine. The leaves of the plant samples were extracted using ethanol and then extracts tested phytochemical content, toxicity, biological activity of antioxidant and antimicrobial. Testing of antioxidant activity by spectrophotometric method using DPPH (1,1-diphenyl-2-picrylhydrazyl), the level of toxicity using by BSLT (Brine Shrimp Lethality Test), and antimicrobials by diffusion method. The results showed is Tapak Leman type has a phytochemical content of alkaloids, flavonoids, tannins, saponis and steroids. Type of Tapak Leman properties is toxic, has strong antioxidant and strong on fungi.
Metrics
References
Bioresearcher. (2013). Indonesian Biodiversity Potential.
Wahyuono S. (2012). Bioactive Evaluation of Medical Plants Colleted From Central Kalimantan. Bagian Biology Pharmacy Department, Faculty of Pharmacy, University of Gadjah mada, Yogyakarta.(Indonesian).
Kähkönen MP, Hopia AI, Vuorela HJ, Rauha JP, Pihlaja K, Kujala TS and Heinonen M. (1999). Antioxidant activity of plant extracts containing phenolic compounds. J Agric Food Chem, 47(10), 3954-3962.
Mammadov R, Ili P and Ertem-Vaizogullar H. (2011). Antioxidant activity and total phenolic content of Gagea fibrosa and Romulea ramiflora. Iran J Chem Chem Eng, 30(3), 57-62.
Sampurno. (2007). Policy of Indonesian natural medicine development. 13th National Seminar on Indonesian Medicinal Plants. Pancasila University, Jakarta. [Indonesian].
Achmad H. (1990). Traditional treatment of rural communities in East Kalimantan. Project Inventory and Cultural Values Development. Project Final Report. Directorate of History and Traditional Values, Directorate General of Culture, Ministry of Education and Culture, Jakarta [Indonesian].
Arunkumar S and Muthuselvam M. (2009). Analysis of phytochemical constituents and antimicrobial activities of Aloe vera L. against clinical pathogens. World J Agric Sci, 5(5), 572-576.
Kokate CK. (2001). Pharmacognosy. 16th ed. Nirali Prakasham, Mumbai, India.
Harborne JB. (2006). Phytochemical Methods, A Guide to Modern Techniques of Plant Analysis. Springer, Netherlands.
Meyer BN, Ferrigni NR, Putman JE, Jacobson LB, Nichols DE and McLaughlin JL. (1982). Brine shrimp: a convenient general bioassay for active plant constituents. Planta Medica, 45(5), 31-34.
Boyd CE. (2005). LC50 calculations help predict toxicity. Global Aquacult Advoc, 84-87.
Wagner SL. (1993). Quarterly Report ofEPA Grant #CR-821022-01, .luly l, 1993 September. 30, 1993. National Pesticide Medical Monitoring Program. Oregon State University, Corvallis.
Arung ET, Muladi S, Sukaton E, Shimizu K and Kondo R. (2008). Artocarpin, a promising compound as whitening agent and anti-skin cancer. J Trop Wood Sci Technol, 6, 33-36.
Jun M, Fu HY, Hong J, Wan X, Yang CS and Ho CT. (20030. Comparison of antioxidant activities of isoflavones from kudzu root (Pueraria lobata Ohwi). J Food Sci, 68(6), 2117-2122.
Cappucino JG and Sherman N. (2001). Microbiology: A Laboratory Manual. 2nd Edition. The Benjamin Cummings Publishing Company. Rockland Community College, State University of New York, New York.
Hanani E, Mun’im A and Sekarini R. (2005). Identifikasi senyawa antioksidan dalam spons Callyspongia sp. dari Kepulauan Seribu. Majalah Ilmu Kefarmasian, 2(3), 127-133.
Evans WC. (2009). Trease and Evans' Pharmacognosy. 16th ed., Saunders Ltd., Edinburgh, UK.
Okwu DE and Ndu CU. (2006). Evaluation of the phytonutrients, mineral and vitamin contents of some varieties of yam. Intl J Mol Med Adv Sci, 12(2), 199-203.
Igwenyi IO, Offor CE, Ajah DA, Nwankwo OC, Ukaomah JI and Aja PM. (2011). Chemical composition of Ipomoea aquatica (green kangkong). Intl J Pharm Biol Sci, 2(4), 593-598.
McLaughlin JL, Chang CJ and Smith DL. (1993). Simple bench-top bioassays (brine shrimp and potato disk) for the discovery of plant antitumor compounds - Review of recent progress. In: Kinghorn AD, Baladrin MF. (eds). Human Medicinal Agents from Plants, Symposium Series No. 534, American Chemical Society, New York.
Dvorak P, Benova K, Žd’arsky M, Sklenar Z and Havelkova A. (2010). Use of the crustacean Artemia franciscana for alternative biotests. Acta Vet Brno 79 (Suppl. 9), 47–53.
McLaughlin. (1991). A Blind Coparison of Simple Bench – top Bioassay and Human Tumour Cel Citotoxicities as Antitumor Prescreens, Natural Product Chemistry, Elsivier, Amsterdam, 1
Cefarelli G, Abrosca BD, Fiorentino A, Izzo A, Mastellone C, Pacifica S and Piscopo V. (2006). Free-radical scavenging and antioxidant activities of secondary metabolites from reddened cv. Annurca apple fruits. J Agric Food Chem, 54(3), 803-809.
Ebrahimzadeh MA, Nabavi SF and Nabavi SM. (2009). Essential oil composition and antioxidant activity of Pterocarya fraxinifolia. Pak J Biol Sci, 12, 957-963.
Saeed N, Khan MR and Shabbir M. (2012). Antioxidant activity, total phenolic and total flavonoid contents of whole plant extract Torilis leptophylla L. BMC Compl Altern Med, 12, 221.
Pan X, Chen F, Wu T, Tang H and Zhao Z. (2009). The acid, bile tolerance and antimicrobial property of Lactobacillus acidophilus NIT. Food Control, 20(6), 598-602.
Sulastrianah Imran and Fitria ES. (2014). Inhibitory test of leaf extracts (Annona muricata L.) and sirih (Piper betle L.) against the growth of Escherichia coli bacteria. Medula 1(2).
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.