Pharmacopoeial comparison of in-process and finished product quality control test for pharmaceutical tablets

Prakash Ghimire; Abinash Chandra Shrestha; Sandhya Pandey; Bidur Chapagain; Samir Dhakal

doi:10.30574/gscbps.2020.11.3.0174

Authors

Prakash Ghimire Universal College of Medical Sciences, Tribhuvan University, Ranigaon, Bhairahawa, Rupandehi, Nepal.
Abinash Chandra Shrestha College of Pharmacy, Woosuk University, Wanju, Jeonbuk 55338, Republic of Korea.
Sandhya Pandey Australian Catholic University, North Sydney, Australia.
Bidur Chapagain Little Buddha College of Health Science, Purbanchal University, Kathmandu, Nepal.
Samir Dhakal Krupanidhi College of Pharmacy, Rajiv Gandhi University, Varthur Hobli, Bangalore, India.

DOI:

https://doi.org/10.30574/gscbps.2020.11.3.0174

Keywords:

In-process quality control, Finished product quality control, Pharmaceutical tablets, Pharmacopoeia, Specification

Abstract

All Pharmaceutical industries endeavour to produce good quality products which are achieved by allowing in-process and finished product quality control approaches. In-process quality control is concepts that are carried out before, after and during production covering all steps, counting the establishment of specifications, sampling, relevant testing and analytical clearance assuring that the intermediates, packaging materials and finished pharmaceutical tablets conform with approved specifications or standard for efficacy, safety and elegance which assure the consumer that the products perform consistently and in a manner satisfactory for the purpose for which it is recommended. Quality control highlights testing of products for defects which ease the producer to refuse the releases of products or carry out the possible investigation to make pharmaceutical tablets perfect before released into the market. Since different pharmacopoeias have set the diverse specified limits to some extent within which the value ought to fall with respect to be acquiescent as per the standards. Hence by comparing pharmacopoeias, an effort is made to convey the harmonized limits so that the products should meet the requirements as specified in pharmacopoeias specification to confirm the quality of pharmaceutical dosage form. The endeavour of this study is to compare various quality control assessments for pharmaceutical tablets according to different pharmacopoeias standards.

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